Found 1410 clinical trials
Time - Lapse Analysis of Frozen Embryos
A retrospective analysis of embryo defrost cycles that were rated in the EmbryoScope system and frozen will be performed. The study will examine the possible association between the morphokinetic grading received by these embryos as fresh embryos before freezing, and their survival, the morphological grading they received after thawing, their …
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- 19 Feb, 2024
- 1 location
Impact of Hypothalamic Gliosis on Appetite Regulation and Obesity Risk in Children
BEAM is a multi-site longitudinal cohort study of hypothalamic gliosis, central regulation of appetite and weight gain in children. Participants will be recruited from the community in the greater Seattle and greater Baltimore area. All participants will consent to enroll in the 24-month study during which they will complete 5 …
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- 19 Feb, 2024
- 2 locations
Immune Biomarkers of Outcome From COVID-19
The investigators will use established techniques to measure immune function that could be rapidly put into routine hospital care to help guide treatment for individual patients.
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- 19 Feb, 2024
- 1 location
Correlation Between Specific Gene Mutationand Local Immune Microenvironment and Immunotherapy Efficacy in NSCLC
Immunotherapy for PD-L1 positive patients is still ineffective in some patientswhich may be related to the complex immune microenvironment.In view of this bottleneck, further refinement of immunotyping and in-depth study of drug resistance mechanism are the most important tasks.
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- 19 Feb, 2024
- 1 location
Scandinavian Diverticulitis Trial SCANDIV-II
Furthermore, the effects on quality of life for this patient group will be evaluated.
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- 19 Feb, 2024
- 1 location
Non-specific Back Pain and Spinal Manipulation
To do this, positive responses to treatment, characterized by improvement in pain score, functional capacity, as well as the global perceived change will be evaluated using single and multiple logistic regressions in which biomechanical variables, comfort, expectation will used as potential predictors.
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- 19 Feb, 2024
- 1 location
Soluble ST2 and Cardiovascular Outcome
Cardiac surgery induces hemodynamic stress on the myocardium, and this process can be associated with significant cardiovascular morbidity and mortality. Soluble suppression of tumorigenicity 2 (sST2) is biomarker of myocardial remodeling and fibrosis; however, little is known regarding their potential association with cardiovascular events.
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- 19 Feb, 2024
- 1 location
Laryngomicrosurgery Under NIDP General Anesthesia Supported by THRIVE
In the present study, with the support of the transnasal humidified rapid-insufflation ventilatory exchange, laryngomicrosurgery would be finished under nonintubated deep paralysis (NIDP) general anesthesia. In this case series study, the investigators will test the safety and feasibility of such a technique.
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- 19 Feb, 2024
- 1 location
Risk of Recurrence of Cervical Artery Dissection During Pregnancy and Puerperium
Many cases of CAD during pregnancy and puerperium have been described, suggesting that pregnancy and puerperium may be potential risk factors for CAD. The purpose of this study is to determine whether pregnancy and puerperium are also recurrence risk factors for CAD.
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- 19 Feb, 2024
- 1 location
Retrospective Chart Review Study of Patients With PIK3CA-Related Overgrowth Spectrum Who Have Received Alpelisib
Patient-level data are abstracted from medical charts of all eligible patients at all participating sites. Information from patients treated with alpelisib will be used to describe the efficacy and safety of alpelisib in PROS patients.
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- 19 Feb, 2024
- 4 locations