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Found 99 clinical trials
COVID - AirPollution

Air pollution may be related to an increase in the COVID-19 severity and lethality through its impact on chronic diseases such as cardiovascular and respiratory diseases and diabetes that are also the main comorbidities associated with COVID-19. Epidemiological studies using individual data are needed to provide more precise estimate of …

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  • 19 Feb, 2024
The Effect and Mechanism of lncRNA NBR2 Regulating Endothelial Pyroptosis by Targeting GSDMD in Sepsis

The dysregulation of lncRNA results in the occurrence and development of tumors, diabetes, sepsis and other diseases. Therefore, we detected lncRNA and mRNA expression profile in 26 blood samples of septic patients using Arraystar LncRNA Microarray.

dysregulated host response
diabetes
cell injury
septicemia
organ failure
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  • 19 Feb, 2024
Mechanisms of Post-Bariatric Hypoglycemia

Post-bariatric hypoglycemia (PBH) is an increasingly recognized syndrome that is incompletely understood. The purpose of this study is to increase our level of understanding by investigating mechanisms contributing to this condition. Participation in this study will take place over four visits, which will include the following Wearing of a continuous …

neuroglycopenia
dietary intervention
hypoglycaemic
antihyperglycemic
continuous glucose monitoring
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  • 19 Feb, 2024
Microvascular Flow and Reactivity in Patients Presenting in the Acute Phase of COVID-19.

Considering that the intensity of systemic microvascular changes in patients in the acute phase of COVID-19 could be related to disease progression and prognosis, the present cross-sectional and observational study aims to investigate the presence of endothelial dysfunction in these patients, also looking for to evaluate associations between the presence …

acute respiratory syndrome (sars)
endothelial dysfunction
covid-19
SARS
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  • 19 Feb, 2024
The COVID-19 Disease and CARdiac Events Study

An observational study of consecutive patients testing positive for COVID-19 who require admission to hospital to determine the degree of myocardial injury through biomarkers and echocardiography and the impact of this on cardiovascular outcomes. The COVID-19 disease and CARdiac Events study (COVICARE).

covid-19
SARS
x-rays
acute respiratory syndrome (sars)
myocardial injury
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  • 19 Feb, 2024
Sequelae of Sars-CoV-2 Infections

By the end of 2019 a new coronavirus, named SARS-CoV-2, was discovered in patients with pneumonia in Wuhan, China. In the following weeks and months the virus spread globally, having a tremendous impact on global health and economy. To date, no vaccine or therapy is available. Severe courses of the …

coronavirus infection
acute respiratory syndrome (sars)
cardiovascular system
pneumonia
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  • 19 Feb, 2024
Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly

Background With the global population aging and life expectancy increasing, dementia has turned a priority in the health care system. In Chile, dementia is one of the most important causes of disability in elderly, corresponding nearly to 40% of cases, and the most rapidly growing cause of death in the …

mild cognitive impairment
cognitive impairment
frontotemporal lobar degeneration
dementia
demented
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  • 19 Feb, 2024
Monitoring of Metabolic Adverse Events of Second Generation Antipsychotics in a Naive Pediatric Population

Introduction: Second Generation Antipsychotics (SGAs) are widely used in the pediatric population. It is currently established that SGAs may induce undesirable metabolic adverse events (AEs) such as weight gain, metabolic changes in blood lipids or glucose with risk of potential cardiovascular morbidity and mortality. The Canadian Alliance for Monitoring Effectiveness …

pediatric
blood test
hematology test
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  • 19 Feb, 2024
Microbiota in COVID-19 Patients for Future Therapeutic and Preventive Approaches

In light of the rapidly emerging pandemic of SARS-CoV-2 infections, the global population and health care systems are facing unprecedented challenges through the combination of transmission and the potential for severe disease. Acute respiratory distress syndrome (ARDS) has been found with unusual clinical features dominated by substantial alveolar fluid load. …

endothelial dysfunction
SARS
lower respiratory tract infection
bronchoalveolar lavage
microbiota
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  • 19 Feb, 2024