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Found 212 clinical trials
Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant

This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.

root canal
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  • 19 Feb, 2024
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Background People with rare cancers often have limited treatment options. The biology of rare cancers is not well understood. Researchers want to find better treatments for these cancers. They want to test 2 drugs that, taken separately, have helped people with non-rare cancers. They want to see if these drugs …

mixed mullerian tumors
gastrointestinal stromal tumor
merkel cell carcinoma
serous cystadenocarcinoma
prostate cancer
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  • 19 Feb, 2024
Dose De-escalation Study of the PI3k Alpha/Delta Inhibitor Copanlisib Given in Combination With the Immunotherapeutic Agents Nivolumab and Rituximab in Patients With Relapsed/Refractory Indolent Lymphoma

Patients with relapsed or refractory follicular or marginal zone lymphoma who have received at least one prior line of therapy will receive Copanlisib IV: day 1, 8, 15 every 28 days Nivolumab IV: Cycle 1 days 1 and 15; then day 1 only Rituximab IV: Cycle 1 days 1, 8, …

indolent lymphoma
endocrine therapy
cirrhosis
marginal zone lymphoma
12 lead electrocardiogram
  • 0 views
  • 19 Feb, 2024
Anti-GITR/Anti-PD1/Stereotactic Radiosurgery in Recurrent Glioblastoma

This is a phase II study of the combination of the GITR agonist monoclonal antibody INCAGN01876, the anti-PD1 monoclonal antibody INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed regimen will be safe and stimulate a robust anti-tumor immune response and result in improved …

gliadel
renal function test
major surgery
tubal ligation
cytotoxic chemotherapy
  • 0 views
  • 19 Feb, 2024
Sentinel Lymph Node Biopsy With Hybrid Technique in Breast Cancer

Sentinel lymph node (SLN) biopsy is the gold standard method to stage axilla in breast cancer. The aim of the study is to compare the efficiency of various methods to identify SLN is breast cancer patients.

sentinel lymph node biopsy
sentinel node
excisional biopsy
  • 0 views
  • 19 Feb, 2024
Honey Products for Cancer Patients With Oral Mucositis: a Randomized Controlled Trial

The investigators plan to conduct a 3-year pioneering care research project for mucositis in cancer patients. These include: (1) an analysis of the incidence and severity of mucositis, severity, treatment methods, and treatment costs; (2) an RCT comparing the effectiveness of honey, Taiwan green propolis, and usual care in mucositis …

cancer
stomatitis
propolis
interleukin-6
neck cancer
  • 0 views
  • 19 Feb, 2024
Taltz in Combination With Enstilar for Psoriasis

Enstilar in combination with Taltz for plaque psoriasis.

vasectomy
hormonal contraception
intrauterine device (iud)
cervical cap
contraceptive sponge
  • 0 views
  • 19 Feb, 2024
A Study of IBI377 in Combination With Corticosteroids for the Treatment of First-Line Acute Graft-Versus-Host Disease

The purpose of this study is to evaluate itacitinib in combination with corticosteroids as first-line treatment of participants with Grade II to IV acute graft-versus-host disease (aGVHD).

cancer
hematologic malignancy
itacitinib
corticosteroids
acute graft versus host disease
  • 0 views
  • 19 Feb, 2024
A Study of BI-1206 in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors (KEYNOTE-A04)

Phase 1/2a Clinical Trial of BI-1206, a Monoclonal Antibody to CD32b (FcRIIB), in Combination with Pembrolizumab in Subjects with Advanced Solid Tumors Previously Treated with Anti-PD-1 or Anti-PD-L1 Antibodies

epidermal growth factor receptor
metastatic melanoma
small cell lung cancer
pembrolizumab
growth factor
  • 0 views
  • 19 Feb, 2024
An Extension Study MRI/US Fusion Imaging and Biopsy in Combination With Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue

To determine the efficacy of using MRI/US fusion imaging technology to direct focal ablation of prostate tissue using nanoparticle-directed laser irradiation.

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  • 19 Feb, 2024