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Found 107 clinical trials
Comparison of High-Dose Rate Brachytherapy and Stereotactic Ablative Radiotherapy as Monotherapy for the Treatment of Localized Prostate Cancer

This phase II trial compares high-dose rate brachytherapy and stereotactic ablative radiotherapy as monotherapy in treating patients with prostate cancer that has not spread to other parts of the body (localized). High-dose rate brachytherapy delivers radiation directly into the prostate within a few minutes by a single radioactive seed through …

adenocarcinoma of prostate
stage iib prostate cancer ajcc v8
transrectal ultrasound
stage iia prostate cancer ajcc v8
MRI
  • 0 views
  • 19 Feb, 2024
  • 2 locations
MRI-guided Focal Laser Ablation

Magnetic resonance imaging-guided focal laser ablation of prostate cancer.

MRI
diffusion weighted imaging
laser ablation
transrectal ultrasound
prostate specific antigen
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CC-94676 in Subjects With Metastatic Castration-Resistant Prostate Cancer

This is a first in human study to assess the safety, tolerability, PK, PD and preliminary efficacy of CC-94676 in men with progressive metastatic castration-resistant prostate cancer.

adenocarcinoma of prostate
androgen suppression
antiandrogen therapy
apalutamide
bilateral orchidectomy
  • 0 views
  • 19 Feb, 2024
  • 6 locations
Study of PSMA PET/MR Guided Stereotactic Body Radiation Therapy With Simultaneous Integrated Boost (SBRT-SIB) for High-Intermediate and High Risk Prostate Cancer

This is a single-arm Phase II clinical trial assessing the clinical efficacy of prostate specific membrane antigen (PSMA) PET/MR guided MR-LINAC based SBRT-SIB with planned accrual of 50 patients.

adenocarcinoma of prostate
stereotactic body radiation therapy
metastasis
adenocarcinoma
hbed-cc
  • 16 views
  • 19 Feb, 2024
  • 1 location
Cost Talk: Discussing Cancer Care Costs

The purpose of this study is to investigate whether an encounter decision aid (used during a consultation) containing cost information about options, combined with clinician training about cost discussions and available financial resources, influence surgeon-patient cost conversations, referrals to address costs, patients' financial stress, and high-quality decision-making for patients with …

cancer care
prostate specific antigen
  • 0 views
  • 19 Feb, 2024
  • 1 location
5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:

5-fraction SABR is a feasible, well-tolerated, effective and cost effective treatment for high-intermediate and high risk prostate cancer with/without an image-guided intraprostatic boost.

adenocarcinoma
adenocarcinoma of prostate
stereotactic body radiation therapy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Adaptive Radiotherapy for Genitourinary Cancers (SMART-B01)

The goal of this clinical trial is to learn if adaptive radiation boost works to treat genitourinary cancers, esp. in the context of prostate cancer patients with post-prostatectomy local relapse and bladder cancer patients with bladder-conserving treatment. It will also learn about the safety and efficacy of adaptive boost.

  • 0 views
  • 08 Jan, 2026
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors  

AGX101 is an antibody-drug conjugate (ADC) therapy for tumor-forming cancers. The purpose of this study is to learn about AGX101 effects and safety at various dose levels in an all-comers advanced solid cancer patient population. AGX101will be administered intravenously.Dosing of AGX101 will be repeated once every 3, 6 or 9 …

  • 0 views
  • 24 Apr, 2026
Tasquinimod for the Treatment of Relapsed or Refractory Myeloma

This study is the first study of tasquinimod, an inhibitor of S100A9, in patients with multiple myeloma.

multiple myeloma
measurable disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
Lutetium-177-PSMA Radioligand Therapy in Advanced Salivary Gland Cancer Patients

Phase 2 pilot study, which evaluates the safety and efficacy of Lutetium-177-PSMA radioligand therapy in advanced salivary gland cancer patients.

gilbert's syndrome
metastasis
neutrophil count
ct scan
adenoid cystic carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location