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Found 1061 clinical trials
4SCAR-T Therapy Post CD19-targeted Immunotherapy

This study will evaluate safety and efficacy of a combination of 4th generation chimeric antigen receptor gene-modified T cells (4SCAR-T) targeting CD19-negative B-ALL that express alternative surface antigens such as CD22, CD10, CD20, CD38, and CD123, as many patients relapse after anti-CD19 immunotherapy. Clinical response and optiminzation of a standardized …

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  • 19 Feb, 2024
Application of LLM Care and Related Affective Computing Systems on People With Parkinson's Disease

To evaluate any physical, cognitive, behavioral, and neuroplastic changes and measure the influence (affective status of participant) of the training on the pathological population, the study utilizes somatometric and neuropsychological assessments and neuroscientific (electroencephalographic, EEG-related) indices, as well as affective computing systems.

diabetes
hypertension
dyskinesia
chronic disease
stiffness
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  • 19 Feb, 2024
The Influence of a Perturbation Training on Balance Recovery of Old Adults: a Randomized Controlled Trial

We also hypothesize that brain function as seen in MRI will be improved in both training methods, more in the random training method. As far as we know, there is a lack of studies investigating the learning effect of random vs.

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  • 19 Feb, 2024
Study of Venetoclax in Combination With Azacytidine in AML Patients Selected Using Ex Vivo Drug Sensitivity Screening

The exploratory study will aim to find novel combinations for overcoming resistance as well as finding/validating biomarkers for both sensitivity and resistance.

cardiac disorder
neoadjuvant therapy
carbon monoxide
acute myeloid leukemia
angina
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  • 19 Feb, 2024
Video-assisted Anal Fistula Treatment (VAAFT) Versus Fistula-tract Laser Closure (Filac) Versus Conventional Seton in the Management of Anal Fistula

Anal fistula is a chronic inflammatory tract connecting an internal opening in the anal canal with one or more than one external openings in the perianal skin Aim of the work This prospective randomized control trial, we will compare video-assisted anal fistula treatment (Vaaft) and Fistula Laser closure (Filac) and …

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  • 19 Feb, 2024
Pectin Use in Pediatric Intestinal Rehabilitation

The study involves patients receiving green beans in their diet for three months with data collection including stooling patterns as well as labs, and then switching over to liquid pectin for three months. Again data collection will take place. The duration of the study once patient is consented is ~6 …

enteral feeding
pediatric
short bowel
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  • 19 Feb, 2024
Comparing the Consolidation Regimens of IDA With Intermediate-dose Cytarabine Versus Intermediate-dose Cytarabine Alone for Elderly AML Patients

This study evaluates Idarubicin (IDA) in combination with the intermediate-dose cytarabine, compared with intermediate-dose cytarabine alone, as a consolidation treatment for elderly AML in first remission.

infarction
arrhythmia
remission
acute promyelocytic leukemia
ejection fraction
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  • 19 Feb, 2024
Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant

This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.

root canal
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  • 19 Feb, 2024
Gated and Non-Gated Dynamic PET/CT Imaging

The goal of this study is to see how the images collected during the first hour compare with the routine images collected as part of the clinical scan.

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  • 19 Feb, 2024
The Positively Quit Trial for Smoking Cessation

People in both groups will receive brief advice to quit and an offer of nicotine replacement therapy patches (NRT), as well as 12 videoconferencing group sessions. We will measure smoking behavior over a one year period and compare smoking rates for the treatment condition against AMC to see if the …

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  • 19 Feb, 2024