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Found 12 clinical trials
Featured trial
Study to Evaluate the Safety and Efficacy of ASC40 in Subjects With Moderate to Severe Acne Vulgaris  

This is a phase2, randomized, double-blind, multi-center, multi-dose and placebo parallel controlled design. The subjects in the study group were given double-blind drugs, and they were taken (orally) after dinner every day according to the requirements of clinical trial scheme.

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  • 2 annotations
  • 19 Feb, 2024
  • 9 locations
Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults

Initially this device will be used in a single-center, open-label, single-arm, phase II clinical trial to evaluate the efficacy of haploidentical PBSC grafts depleted of TCR/+ and CD19+ cells using the CliniMACS TCR/CD19 System in children and adults with hematological and non-hematological malignancies.

direct bilirubin
congestive heart failure
graft versus host disease
alt/ast
hla-a
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  • 19 Feb, 2024
Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen

Patients eligible for this study have a type of blood cancer Acute Myeloid Leukemia (AML) which has come back or has not gone away after treatment. The body has different ways of fighting disease and infection, and this research study combines two different ways of fighting cancer with antibodies and …

leukemia
lymphoma
aptt
myeloid leukemia
apheresis
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  • 19 Feb, 2024
Expanded Access of Omidubicel for Allogeneic Transplantation in Patients With Hematological Malignancies

Omidubicel is an investigational therapy for patients with high-risk hematologic malignancies.

hematologic malignancy
cancer
investigational treatment
allogeneic transplantation
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  • 19 Feb, 2024
Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis

This phase II trial studies how well infliximab and intravenous immunoglobulin therapy work in treating patients with pneumonitis that does not respond to steroid treatment. Immunotherapy with monoclonal antibodies such as, infliximab, may induce changes in body's immune system and may interfere with the ability of tumor cells to grow …

herpes
methylprednisolone
hematopoietic and lymphoid cell neoplasm
steroid treatment
immunoglobulin
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  • 19 Feb, 2024
A Study of CT-RD06 Cell Injection in Patients With Relapsed or Refractory CD19+ B-cell Hematological Malignancy

A study of CT-RD06 cell injection in patients with relapsed or refractory CD19+ B-cell hematological malignancy.

lymphoma
b-cell acute lymphoblastic leukemia
lymphoblastic leukemia
hematologic malignancy
chronic lymphocytic leukemia
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  • 19 Feb, 2024
A Study of CTA101 UCAR-T Cell Injection in Patients With Relapsed or Refractory CD19+ B-line Hematological Malignancy

A study of CTA101 UCAR-T cell injection in patients with relapsed or refractory CD19+ B-line hematological malignancy

lymphoma
b-cell acute lymphoblastic leukemia
autologous hematopoietic stem cell transplant
lymphoblastic leukemia
hematologic malignancy
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  • 19 Feb, 2024
A Study of CD20/CD22 Targeted CAR T-cell Therapy for Relapsed or Refractory Lymphoid Malignancies

A Study of CD20/CD22 Targeted CAR T-cell Therapy for Relapsed or Refractory Lymphoid Malignancies.

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  • 19 Feb, 2024
Collection of Biological Samples From Patients Treated With CAR-T Cells for Hematological Malignancies

This project aims to bank blood samples from a cohort of patients treated with CAR-T cell for hematological malignancies in Montpellier University Hospital. Clinical data related to samples will be collected. This samples will be used to determine factors influencing efficacy of CAR-T cells treatments.

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  • 19 Feb, 2024
Register of Blood Stem Cell Transplantation

Register of patients with blood stem cell transplantations (autologous, allogen).

cell transplantation
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  • 19 Feb, 2024