Found 1062 clinical trials
l Investigation of Robotic-assisted TKA (RA-TKA) With Skywalker and Evolution Medial Pivot Knee (eMP Knee) (123)
This is a prospective trial that attempts to develop evidence on the safety and performance of RA-TKA (Robotic-assisted total knee arthroplasty) with Skywalker and eMP (Evolution Medial Pivot) knee. Moreover to evaluate performance of eMP patients with Skywalker (in comparison to eMP with conventional instrumentations and non-MP TKAs)
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- 19 May, 2025
- Online study
Individualizing Treatment for Asthma in Primary Care (Full Study) (iTREAT-PC)
This study will compare two currently available approaches to reduce AEX in primary care patients: (1) use of inhaled corticosteroids (ICS) as part of rescue therapy, also known as MART (Maintenance And Reliever Therapy) or PARTICS (Patient Activated Reliever Trigger Inhaled Corticosteriods) therapy - either of these therapies will be …
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- 24 Nov, 2025
- 7 locations
Diffusion MRI for Head and Neck Cancer
However, it is often underappreciated that these dMRI metrics are not fixed constants, but rather functions of the diffusion time t, D(t) and K(t); their t-dependency is determined by tissue properties, such as cell size and membrane permeability of tissue. D(t) and K(t) of tumors can vary substantially depending on …
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- 29 Jul, 2025
- 2 locations
Neoadjuvant SHR-1701 Plus Chemoradiotherapy for Locally Advanced Rectal Cancer (MA-CRC-II-018)
The goal of this clinical trial is to learn if SHR-1701 combine with chemoradiotherapy works to treat severe CRC.Participants will take:Induction: SHR-1701 combined with CAPOX for one cycle. Radiotherapy: Short-course radiotherapy (SCRT) (25Gy/5F). Consolidation: SHR-1701 combined with CAPOX for five cycles, after which the subjects undergo TME surgery.
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- 18 Mar, 2026
- 2 locations
Study to test asthama
To determine the etiology and clinical presentation of increased serum ammonia in infants and children presented to the Pediatric Genetic unit, Assiut University Hospital-To study the effects of certain precautions on serum ammonia levels.
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- 07 Mar, 2025
- 1 location
A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma
A Phase I study to evaluate the safety of a novel, orally available, selective, and potent small molecule inhibitor of the histone lysine methyl transferase MMSET (also known as NSD2/WHSC1) to prevent the dimethylation of H3K36 in adult patients with relapsed or refractory multiple myeloma (RRMM).
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- 24 Nov, 2025
- 18 locations
Switch Maintenance in Pancreatic
The names of the study drugs involved in this study are:Domvanalimab (also known as AB154)Zimberelimab (also known as AB122)APX005M
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- 24 Nov, 2025
- 1 location
Cirtuvivint in Selected Advanced Soft-Tissue Sarcomas (CIRTUSARC)
The study is a Phase 2 clinical trial of the drug cirtuvivint as a second-line treatment for advanced soft tissue sarcomas. The study is being conducted in Spain and is expected to enroll approximately 25 patients in total.
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- 24 Jun, 2025
- 1 location
TriPRIL CAR T Cells in Multiple Myeloma
TriPRIL CAR T CellsFludarabine and Cyclophosphamide: Standardly used chemotherapy drugs as part of lymphodepleting process
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- 24 Nov, 2025
- 1 location
Auricular Acupressure for Premenstrual Syndrome in Female Students
This has led to increasing interest in alternative treatments such as traditional medicine. Auricular acupressure, a non-invasive and low-risk method, has shown promising results in managing PMS symptoms and is gaining attention as a possible solution.
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- 30 Nov, 2025
- 4 locations