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Found 11 clinical trials
SAR408701 Versus Docetaxel in Previously Treated Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients  

Primary Objectives: Study is designed with two primary endpoints that will be analyzed on randomized participants at the time of the cutoff date for each given analysis (progressive free survival [PFS] and overall survival [OS]). Study success is defined either on PFS or OS The primary objective is to determine …

non-small cell lung cancer
immune checkpoint inhibitor
platinum-based chemotherapy
small cell lung cancer
non-squamous non-small cell lung cancer
  • 0 views
  • 19 Feb, 2024
  • 52 locations
Reconstruction of Atrophic Maxillary Ridges Using Mandibular Blocks With and Without Coverage Using Collagen Membrane

Is the use of collagen membrane on top of particulate bone mixture covered by onlay bone block in Maxilla better than the use of mixture of particulate bone covered by onlay bone block without the use of collagen membrane, in terms of bone quality and bone quantity?

  • 0 views
  • 19 Feb, 2024
Multi-4SCAR-T Therapy Targeting Breast Cancer

The purpose of this study is to assess the feasibility, safety and efficacy of multiple 4th generation CAR-T cells targeting Her2, GD2, and CD44v6 surface antigen in breast cancer. Another goal of the study is to learn more about the activities of the multi-CAR T cells and their persistency in …

immunosuppressive agents
serum bilirubin
immunosuppression
neutrophil count
  • 2 views
  • 19 Feb, 2024
SAR408701 Versus Docetaxel in Previously Treated Carcinoembryonic Antigen-related Cell Adhesion Molecule 5 (CEACAM5) Positive Metastatic Non-squamous Non-small Cell Lung Cancer Patients

Primary Objectives: Study is designed with two primary endpoints that will be analyzed on randomized participants at the time of the cutoff date for each given analysis (progressive free survival [PFS] and overall survival [OS]). Study success is defined either on PFS or OS The primary objective is to determine …

non-small cell lung cancer
immune checkpoint inhibitor
platinum-based chemotherapy
small cell lung cancer
non-squamous non-small cell lung cancer
  • 0 views
  • 19 Feb, 2024
  • 169 locations
Prospective Clinical Trial of Onlay-carrying Patients

A record of the type of onlay will be made with respect to its extension, tooth or teeth to be treated, the material of clothing and the substrate on which the adhesion and cementing method, as well as the type of antagonist. To complete it, a complete clinical oral examination …

  • 0 views
  • 19 Feb, 2024
The Use of plasmaJet During Operative Laparoscopy for Endometriosis

Therefore, the use of ultrasound, laser or plasma energy can potentially reduce damage to surrounding tissues and prevent adhesion formation. In addition, ablation of the internal surface of endometriomas can be an effective alternative to cystectomy. The PlasmaJet system uses argon plasma which is released as kinetic, light and / …

endometriosis
laparoscopy
endometrioma
adhesion
  • 0 views
  • 19 Feb, 2024
Internal Limiting Membrane Peeling in Proliferative Diabetic Retinopathy

Subject/Participant Groups: Study Group: Subjects undergo internal limiting membrane (ILM) peeling during vitrectomy for the indication of tractional retinal detachment Control Group: Subjects do not undergo ILM peeling during vitrectomy for the indication of tractional retinal detachment

diabetes
diabetic retinopathy
retinopathy
proliferative diabetic retinopathy
detachment
  • 0 views
  • 19 Feb, 2024
Effect of Nutritional Supplementation and Pulmonary Rehabilitation on the Clinical Status of HF and COPD

Cardiovascular diseases (CVD) are the leading cause of death in the world and our country. The prevalence of Heart Failure (HF) is 1-2% in the adult population in developed countries, up to 10% among people 70 years of age. Concerning COPD, it is estimated that by 2030 will be the …

lung disease
leucine
bronchodilator
post bronchodilator spirometry
pulmonary function tests
  • 0 views
  • 19 Feb, 2024
Biomarkers in Polyradiculoneuropathies

The investigators found that antibodies target cell adhesion molecules at nodes of Ranvier in 10% of patients with chronic inflammatory demyelinating neuropathy (CIDP), another disabling neuromuscular disease affecting peripheral nerves.

fibres
neuropathy
guillain-barre syndrome
neuromuscular diseases
polyradiculoneuropathy
  • 0 views
  • 19 Feb, 2024
Microvascular Flow and Reactivity in Patients Presenting in the Acute Phase of COVID-19.

Considering that the intensity of systemic microvascular changes in patients in the acute phase of COVID-19 could be related to disease progression and prognosis, the present cross-sectional and observational study aims to investigate the presence of endothelial dysfunction in these patients, also looking for to evaluate associations between the presence …

SARS
covid-19
acute respiratory syndrome (sars)
endothelial dysfunction
  • 0 views
  • 19 Feb, 2024