Colchester, Vermont Clinical Trials

A listing of Colchester, Vermont clinical trials actively recruiting patient volunteers.

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Found 25 clinical trials
Social & QoL Behaviors in Parkinson's Disease

Adults with Parkinson's Disease experience an array of challenges and changes in daily living, behaviors, and functioning throughout the progression of their condition. The investigators want to learn more about the effects of Parkinson's Disease on individuals' social behavior and quality of life (QoL) compared to people of the same …

Online studies
Accepts healthy volunteers
  • 0 views
  • 02 Apr, 2026
  • Online study
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

hemodynamic evaluation
macitentan
heart disease
right heart catheterization
connective tissue disease
University of Vermont Medical Center
 (5.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +210 other locations
Phase 2 Study of SAR439859 Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer (AMEERA-3)

Primary Objective: To determine whether SAR439859 per os improves progression free survival (PFS) when compared with a endocrine monotherapy of the choice of the physician, in participants with metastatic or locally advanced breast cancer. Secondary Objectives: To compare the overall survival in the 2 treatment arms To assess the objective …

estrogen receptor-positive breast cancer
targeted therapy
letrozole
breast cancer
anastrozole
Investigational Site Number 8400026
 (2.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +130 other locations
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis (FREVIVA)  

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the disability progression and the safety up to approximately 51 months administration of study intervention compared to placebo in male and female participants with nrSPMS (aged 18 to 60 years at …

University Of Vermont Site Number : 8400042
 (2.7 away)
  • 0 views
  • 04 Mar, 2025
  • +58 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

cytokines
solid tumor
glomerular filtration rate
percutaneous endoscopic gastrostomy
ascites
University of Vermont and State Agricultural College
 (2.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations