Charlottesville, Virginia Clinical Trials

A listing of Charlottesville, Virginia clinical trials actively recruiting patient volunteers.

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Found 35 clinical trials
UAT_Local 01-19-May  

This is for UAT_Local 01-19-May.

Accepts healthy volunteers
Online studies
UAT-UK
(online study)
  • 0 views
  • 19 May, 2025
  • 1 location
  • Online study
Test

In this prospective cohort study, 250 patients with suspected or known CAD and at least one intermediate coronary lesion (50-70% stenosis) who had a NiFFR value greater than 0.80 underwent coronary computed tomography angiography (CCTA) with NiFFR assessment. Patients were followed for one year to monitor for MACE

Online studies
  • 0 views
  • 28 Aug, 2025
  • Online study
Social & QoL Behaviors in Parkinson's Disease

Adults with Parkinson's Disease experience an array of challenges and changes in daily living, behaviors, and functioning throughout the progression of their condition. The investigators want to learn more about the effects of Parkinson's Disease on individuals' social behavior and quality of life (QoL) compared to people of the same …

Accepts healthy volunteers
Online studies
  • 0 views
  • 02 Apr, 2026
  • Online study
MMAPPIN' Study: Multiple Myeloma Analysis For Patient-specific Insights to Dissect Disease Heterogeneity

This is a single-center, observational study in patients with multiple myeloma, conducted both retrospectively and prospectively. The study aims to improve understanding of the biological and clinical factors that influence disease progression, relapse, and treatment resistance.The study will integrate clinical information with advanced genomic and molecular analyses, including whole genome …

Online studies
  • 0 views
  • 15 Jul, 2026
  • Online study
Enfortumab Vedotin and Pembrolizumab With or Without Chemotherapy vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together alone or with platinum chemotherapy to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients …

cancer
metastatic urothelial carcinoma
external beam radiation therapy
measurable disease
enfortumab vedotin
University of Virginia
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +25 other locations
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)

This is a global Phase 2, open-label, single-arm, multicohort, multicenter study to evaluate efficacy and safety of JCAR017 in adult subjects with r/r FL or MZL. The study will be conducted in compliance with the International Council on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good …

hodgkin's disease
b-cell lymphoma
malt
non-hodgkin lymphoma
refractory follicular lymphoma
University of Virginia Health System
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +35 other locations
Neoadjuvant Endocrine Therapy Tolerance in Geriatric Early Stage ER+ Breast Cancer

This single arm pilot study evaluates the use of neoadjuvant endocrine therapy in women with early stage ER+ breast cancer who are 70 years or older and are scheduled to have breast conservation surgery (BCS). The purpose of this study is to see if tolerance of neoadjuvant endocrine therapy helps …

HER2
aromatase inhibitor
tamoxifen
hormone therapy
cancer
University of Virginia
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
2019-06 TRISCEND Study

Early feasibility study to assess safety and performance of the Edwards EVOQUE Tricuspid Valve Replacement System

medical therapy
tricuspid valve replacement
University of Virginia Health System
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Hyperpolarized Imaging for New Treatments

The introduction of triple combination CFTR modulator therapy for patients with Cystic Fibrosis (CF) with at least one copy of the deltaF508 mutation is expected to provide major health benefits, but will also require novel outcome measures that can detect CF lung disease at an early stage, capture the efficacy …

cystic fibrosis transmembrane conductance regulator
cystic fibrosis
pilocarpine
multiple breath washout
fibrosis
University of Virginia School of Medicine
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
EBRT and HDR Brachytherapy for Unfavorable-intermediate High and Very High-risk Prostate Cancer

This study is trying to find out if the combination of Androgen deprivation therapy (ADT), MRI guided high dose radiation (HDR) brachytherapy treatment (internal radiation implant procedure) and external beam radiation therapy (EBRT) treatments lead to less side effects. This study is also looking at patient outcomes, quality of life, …

prostate cancer
androgen suppression
cancer
adenocarcinoma
external beam radiation therapy
University of Virginia
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location