Charlottesville, Virginia Clinical Trials

A listing of Charlottesville, Virginia clinical trials actively recruiting patient volunteers.

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Found 34 clinical trials
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In this prospective cohort study, 250 patients with suspected or known CAD and at least one intermediate coronary lesion (50-70% stenosis) who had a NiFFR value greater than 0.80 underwent coronary computed tomography angiography (CCTA) with NiFFR assessment. Patients were followed for one year to monitor for MACE

Online studies
  • 0 views
  • 28 Aug, 2025
  • Online study
Shweta - Protein and Polycystic Ovary Syndrome (PCOS)  

Polycystic ovary syndrome (PCOS) is a significant public health problem and is one of the most common hormonal disturbances affecting women of reproductive age. Women with PCOS are often insulin resistant, increasing their risk for cardiometabolic health problems (e.g., type 2 diabetes, heart disease, high blood pressure, sleep apnea, anxiety, …

Online studies
Accepts healthy volunteers
  • 0 views
  • 24 Apr, 2026
  • Online study
Social & QoL Behaviors in Parkinson's Disease

Adults with Parkinson's Disease experience an array of challenges and changes in daily living, behaviors, and functioning throughout the progression of their condition. The investigators want to learn more about the effects of Parkinson's Disease on individuals' social behavior and quality of life (QoL) compared to people of the same …

Online studies
Accepts healthy volunteers
  • 0 views
  • 02 Apr, 2026
  • Online study
Enfortumab Vedotin and Pembrolizumab With or Without Chemotherapy vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together alone or with platinum chemotherapy to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients …

pd-l1
systemic therapy
immunomodulator
immunomodulators
carboplatin
University of Virginia
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +25 other locations
A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL)

This is a global Phase 2, open-label, single-arm, multicohort, multicenter study to evaluate efficacy and safety of JCAR017 in adult subjects with r/r FL or MZL. The study will be conducted in compliance with the International Council on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use/Good …

malt
systemic therapy
fludarabine
b-cell lymphoma
alkylating agents
University of Virginia Health System
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +35 other locations
Neoadjuvant Endocrine Therapy Tolerance in Geriatric Early Stage ER+ Breast Cancer

This single arm pilot study evaluates the use of neoadjuvant endocrine therapy in women with early stage ER+ breast cancer who are 70 years or older and are scheduled to have breast conservation surgery (BCS). The purpose of this study is to see if tolerance of neoadjuvant endocrine therapy helps …

tamoxifen
HER2
breast cancer
aromatase inhibitor
letrozole
University of Virginia
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
2019-06 TRISCEND Study

Early feasibility study to assess safety and performance of the Edwards EVOQUE Tricuspid Valve Replacement System

tricuspid valve replacement
medical therapy
University of Virginia Health System
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Hyperpolarized Imaging for New Treatments

The introduction of triple combination CFTR modulator therapy for patients with Cystic Fibrosis (CF) with at least one copy of the deltaF508 mutation is expected to provide major health benefits, but will also require novel outcome measures that can detect CF lung disease at an early stage, capture the efficacy …

cystic fibrosis transmembrane conductance regulator
antibiotic therapy
multiple breath washout
sweat test
sweat chloride test
University of Virginia School of Medicine
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
EBRT and HDR Brachytherapy for Unfavorable-intermediate High and Very High-risk Prostate Cancer

This study is trying to find out if the combination of Androgen deprivation therapy (ADT), MRI guided high dose radiation (HDR) brachytherapy treatment (internal radiation implant procedure) and external beam radiation therapy (EBRT) treatments lead to less side effects. This study is also looking at patient outcomes, quality of life, …

pelvic mri
androgens
digital rectal examination
antiandrogen therapy
adenocarcinoma of prostate
University of Virginia
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

eliglustat
imiglucerase
gaucher disease
deficiency
Investigational Site Number 840078
 (5.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +220 other locations