Houston, Texas Clinical Trials

A listing of Houston, Texas clinical trials actively recruiting patient volunteers.

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Found 94 clinical trials
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

dementia
aphasia
progranulin
pick's disease
Houston Methodist Institute for Academic Medicine
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +46 other locations
FDG PET-MRI for the Diagnosis of Spinal Cord Lesions

This trial studies the best time point of using F18-FDG that gives the best image on PET-MRI in patients with spinal cord lesions of unknown cause. Diagnostic procedures, such as F18-FDG PET-MRI, may help find and diagnose spinal cord lesions.

spinal cord
positron emission tomography
M D Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
An Efficacy and Safety Study of Ravulizumab in ALS Participants

The purpose of the study is to assess the efficacy and safety of ravulizumab for the treatment of adult participants with ALS.

ravulizumab
edaravone
vaccination
riluzole
Nerve & Muscle Center of Texas
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

thoracoscopy
folic acid
cancer
lung cancer
wedge excision
MD Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
FT596 as a Monotherapy and in Combination With Anti-CD20 Monoclonal Antibodies

This is a Phase I dose-finding study of FT596 as monotherapy and in combination with Rituximab or Obinutuzumab in subjects with relapsed/refractory B-cell Lymphoma or Chronic Lymphocytic Leukemia. The study will consist of a dose-escalation stage and an expansion stage where participants will be enrolled into indication-specific cohorts.

monoclonal antibodies
contraceptive use
lymphocytic leukemia
leukemia
b-cell lymphoma
MD Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Early Feasibility Study: Fetoscopic NEOX Cord 1K Myelomeningocele (MMC) Repair

The purpose of this study is to test the feasibility of surgically covering myelomeningocele spina bifida spinal cord developmental defects using Neox Cord 1K, cryopreserved human umbilical cords, via a laparotomy-fetoscopic surgical approach. Intact repair of the defect, prevention of cerebral spinal fluid leakage and wound dehiscence will be assessed …

spina bifida
body mass index
spinal cord disease
kyphosis
myelomeningocele
The University of Texas Health Science Center at Houston
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS CMML or AML

Study ASTX030-01 is designed to move efficiently from Phase 1 to Phase 3. Phase 1 consists of an open-label Dose Escalation Stage (Stage A) using multiple cohorts at escalating dose levels of oral cedazuridine and azacitidine (only one study drug will be escalated at a time) followed by a Dose …

chronic myeloid leukemia
conjugated bilirubin
chronic myelomonocytic leukemia
acute myeloid leukemia
myelodysplastic/myeloproliferative neoplasm
MD Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

This phase I/II trial studies the side effects and best dose of avelumab with M6620 in treating patients with deoxyribonucleic acid (DNA) damage repair (DDR) deficient solid tumors that have spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable). DDR deficiency refers to a …

biopsy
monoclonal antibodies
CHEK2
absolute neutrophil count
metastatic castration-resistant prostate cancer
M D Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

The purpose of the study is to test how well patients with advanced solid tumors and ovarian cancer respond to treatment with BAY1895344 in combination with niraparib. In addition researchers want to find for patients the optimal dose of BAY1895344 in combination with niraparib, how the drug is tolerated and …

tumor cells
cancer
serum pregnancy test
platelet count
measurable disease
University of Texas MD Anderson Cancer Center
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

solid tumor
HER2
gastric tumor
cancer
advanced malignant solid tumor
Bolt Investigative Site
 (4.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations