Dallas & Murphy, Texas Clinical Trials

A listing of Dallas & Murphy, Texas clinical trials actively recruiting patient volunteers.

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Found 69 clinical trials
Cerebellar tDCS in Children With Autism Spectrum Disorder

The purpose of this research study is to investigate whether tDCS to the cerebellum (specifically, the right crus I/II area of the cerebellum) of children and young adults with autism spectrum disorders (ASD) is safe and to examine its effects on some of the symptoms of ASD, such as repetitive …

transcranial direct current stimulation
pervasive developmental disorder
autism
University of Texas Southwestern
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
HYPORT: A Phase I/II Study of Hypofractionated Post-operative Radiation Therapy for Head and Neck Cancer

There is a strong radiobiological and economic rationale for hypofractionated radiation therapy in head and neck cancer. Phase 1 of the trial aims to assess the acute toxicity and tolerability of hypofractionated radiation therapy in the post-operative setting, and to determine the dose/fractionation for Phase 2. Phase 2 aims to …

complete resection
perineural invasion
squamous cell carcinoma of the oral cavity
unstable angina
intensity-modulated radiation therapy
University of Texas Southwestern Medical Centers
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study Evaluating JUV DERM VOLUMA XC Injectable Gel for Correction of Temple Hollowing in Adult Participants Over 22 Years Old

The objectives of this study are to evaluate the safety and effectiveness of Juvederm Voluma XC injectable gel in adult participants seeking correction of temple hollowing

Dallas Plastic Surgery Institute
 (7.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +14 other locations
Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia

This study will evaluate safety, tolerability, and preliminary efficacy of a single intravitreal (IVT) injection of a recombinant adeno-associated virus (AAV) gene therapy, 4D-110, in male patients with genetically-confirmed Choroideremia (CHM).

Retina Foundation of the Southwest
 (9.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)

This is a Phase Ib/II study to evaluate the safety and efficacy of autologous T cells engineered with a chimeric antigen receptor (CAR) targeting CD19 in adult patients with relapsed or refractory B cell acute lymphoblastic leukemia (ALL).

Baylor Scott & White Research Institute
 (1.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +29 other locations
Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) Before and During Treatment With Ocrelizumab

This is an open-label, multicenter study that includes a main study for all participants enrolled and an optional cerebrospinal fluid (CSF) sub-study. Self-identified African American (AA) and Hispanic or Latin American (HA) participants with a diagnosis of relapsing multiple sclerosis (RMS) will be enrolled. The treating neurologist must make an …

MS Treatment Center of Dallas
 (1.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +30 other locations
AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom)

This is a Phase 1/2, open-label, multiple-center, dose escalation and cohort expansion study to evaluate the safety and efficacy of NGGT002 in adult subjects with classic Phenylketonuria (PKU). NGGT002 is an rAAV8 based vector carrying a functional copy of the human PAH gene.Participants will receive a single administration of NGGT002 …

University or Texas, Southwestern medical Center
 (3.4 away) Contact site
  • 0 views
  • 09 May, 2025
  • +1 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
cardiovascular disease
tirzepatide
body mass index
Cardiovascular Research Institute of Dallas
 (7.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

alzheimer's disease
positron emission tomography
mini-mental state examination
flortaucipir
florbetapir
Baylor AT&T Memory Center
 (7.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

treatment regimen
lasmiditan
migraine
ly573144
preventive medication
University of Texas Southwestern Medical Center at Dallas
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +162 other locations