Lincoln, Rhode Island Clinical Trials

A listing of Lincoln, Rhode Island clinical trials actively recruiting patient volunteers.

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Found 35 clinical trials
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

apolipoprotein e4
mini-mental state examination
mental state examination
alzheimer's disease
Accepts healthy volunteers
Butler Hospital Memory and Aging Program
 (5.3 away) Contact site
  • 32 views
  • 20 Sep, 2024
  • +126 other locations
A Study of Copanlisib Combined With Rucaparib in Patients With Metastatic Castration-resistant Prostate Cancer

This is a single arm Phase Ib/II, open label, safety, pharmacokinetic and efficacy clinical study in adult patients with metastatic castration-resistant prostate cancer (mCRPC). Patients will be treated with the combination of copanlisib and rucaparib for as long as the patient does not have clinically significant progressive disease and/or unacceptable …

hba1c
lipase
glycosylated hemoglobin
fancl
apalutamide
Lifespan Cancer Institute
 (6.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Teaching Novel Values-Based Skills to Improve Long-Term Weight Loss

This NIDDK funded R01 project is a randomized controlled clinical trial to compare the efficacy of an intervention based on Acceptance and Commitment Therapy (ACT) and a Self-Regulation (SR) intervention on weight loss maintenance over a 30-month period. All participants will first complete a well-validated online weight loss intervention (months …

body mass index
acceptance and commitment therapy
Weight Control and Diabetes Research Center
 (6.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Culturally Centered CBT for Latinx Youth

The primary aim of the proposed research is to test the effect of a culturally centered treatment protocol, the Socio-cognitive behavioral therapy (SCBT), versus Treatment as Usual on suicidal thoughts and attempts, and depressive symptoms, in a clinical sample of Latinx adolescents. The study is trying to determine, if we …

cognitive therapy
behavior therapy
depressive symptoms
suicide
suicidal
Hasbro Children's Hospital (Inpatient Psychiatric Unit)
 (6.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With BAN2401 in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

The primary purpose of this study is to determine whether treatment with BAN2401 is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Trial) and to determine whether treatment with BAN2401 is superior to placebo in reducing brain …

Butler Hospital Memory and Aging Program
 (5.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Strength for U in Relationship Empowerment

The objective of this study is to test whether the innovative intervention, "Strength for U in Relationship Empowerment" (SURE), reduces the frequency of IPV more than an attention, time, and information matched control condition in perinatal women seeking mental health care.

drug use
Women and Infants Hospital of Rhode Island
 (8.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
The Rhode Island Prescription and Illicit Drug Study

This study will test the efficacy of a novel drug-checking intervention to prevent fatal and non-fatal overdose among people who use drugs (PWUD), who are 18-65 years old at the time of enrollment. The investigators will evaluate whether the incorporation of rapid fentanyl testing into a theory-driven overdose education and …

drugs of abuse
heroin
stimulants
Brown University School of Public Health
 (5.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Fourth Trimester - A Web-based Tool for Postpartum Care to Address the Needs of Underserved Women

The postpartum period is a critical time for both maternal and child health, and more than half of all maternal deaths occur postpartum, from one day to one year after birth. This poor outcome is linked to the racial and ethnic disparities that disproportionately effects low income and black women. …

Orange Square Design Inc.
 (3.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Dose Escalation of DF6002 in Patients With Advanced Solid Tumors and Expansion in Selected Indications

This study is a Phase 1/2, open-label, dose-escalation study with a consecutive parallel-group efficacy expansion study, designed to determine the safety, tolerability, PK, pharmacodynamics, and preliminary anti-tumor activity of DF6002 as monotherapy and in combination with pembrolizumab.

programmed cell death 1 ligand 1
non-small cell lung cancer
platinum-based chemotherapy
renal function
lymphoma
Rhode Island Hospital
 (6.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

eliglustat
gaucher disease
deficiency
imiglucerase
Investigational Site Number 840053
 (6.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +220 other locations