Wynnewood, Pennsylvania Clinical Trials

A listing of Wynnewood, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 102 clinical trials
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
body mass index
cardiovascular disease
tirzepatide
Thomas Jefferson University
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

sarcoma
recurrent endometrial cancer
maintenance therapy
measurable disease
cancer therapy
Research Site
 (9.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
flortaucipir
mini-mental state examination
florbetapir
alzheimer's disease
University of Pennsylvania Heath System
 (5.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
PCSK9i in AAA12

Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol

Hospital Test2a
 (5.1 away) Contact site
  • 0 views
  • 21 Nov, 2024
  • 1 location
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

aphasia
progranulin
pick's disease
dementia
University of Pennsylvania
 (5.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +46 other locations
Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Evaluate the safety and tolerability of AMG 509 in adult subjects and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

neutrophil count
antiandrogen therapy
serum testosterone
orchiectomy
metastasis
Research Site
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
Niraparib/TTFields in GBM

Evaluating the efficacy and safety of niraparib and Tumor-Treating Fields (TTFields) in recurrent glioblastoma (GBM).

karnofsky performance status
MRI
recurrent glioblastoma
tumor treating fields therapy
glioblastoma
Hospital of the University of Pennsylvania
 (5.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

lung cancer
wedge resection
pulmonary resection
folic acid
thoracic surgery
University of Pennsylvania
 (5.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
Accelerometer Sensing for Micra AV Study

The purpose of the AccelAV Study is to characterize chronic AV synchrony in subjects implanted with MicraTM AV device. This study will be conducted upon market approval of the MicraTM AV Transcatheter Pacing System.

atrioventricular block
Thomas Jefferson University
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication

Prospective, multi-center, non-randomized study with consecutive, eligible subject enrollment at each site, for the evaluation of the ChEVAS System for Endovascular Repair of Complex Abdominal Aortic Aneurysms.

Cooper University Hospital
 (9.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations