Rockledge, Pennsylvania Clinical Trials

A listing of Rockledge, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 63 clinical trials
Study of CPI-006 as Immunotherapy for Hospitalized COVID-19 Patients

This Phase 1 single-dose, dose-escalation study is an open label trial evaluating the safety of CPI-006, a humanized monoclonal antibody targeting the CD73 cell-surface ectonucleotidase, as immunotherapy for stable hospitalized mild or moderately symptomatic COVID-19 patients.

nasopharyngeal swab
SARS
cancer
monoclonal antibodies
nasal swab
Temple University Hospital
 (5.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

hypothermia
life support
cardiac arrest
resuscitation
induced hypothermia
Temple University Hospital
 (5.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
body mass index
cardiovascular disease
tirzepatide
Northeast Endocrine Metabolic Associates
 (4.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

sarcoma
recurrent endometrial cancer
maintenance therapy
measurable disease
cancer therapy
Research Site
 (10.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
flortaucipir
mini-mental state examination
florbetapir
alzheimer's disease
Clinical Trial Center, LLC, Psychiatry
 (2.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Evaluate the safety and tolerability of AMG 509 in adult subjects and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

neutrophil count
antiandrogen therapy
serum testosterone
orchiectomy
metastasis
Research Site
 (9.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
Accelerometer Sensing for Micra AV Study

The purpose of the AccelAV Study is to characterize chronic AV synchrony in subjects implanted with MicraTM AV device. This study will be conducted upon market approval of the MicraTM AV Transcatheter Pacing System.

atrioventricular block
Thomas Jefferson University
 (9.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication

Prospective, multi-center, non-randomized study with consecutive, eligible subject enrollment at each site, for the evaluation of the ChEVAS System for Endovascular Repair of Complex Abdominal Aortic Aneurysms.

Cooper University Hospital
 (10.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
A Study of SY 5609 a Selective CDK7 Inhibitor in Advanced Solid Tumors

This is a dose escalation study and will be the first to administer SY-5609 alone to humans with select advanced solid tumors and in combination with Fulvestrant to patients with HR positive, HER2-negative breast cancer.

health screening
solid tumor
cancer
stage iv breast cancer
human chorionic gonadotropin
Sidney Kimmel Cancer Center
 (9.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
Wells and Enteric Disease Transmission Trial (WET - Trial)

Approximately 40 million people in the US are served by private wells, many of which are untreated. The investigators estimate that 1.29 million cases of gastrointestinal illness (GI) per year are attributed to consuming water from untreated private wells in the US. These cases of GI can cause a significant …

Temple University
 (7.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location