Elkins Park, Pennsylvania Clinical Trials

A listing of Elkins Park, Pennsylvania clinical trials actively recruiting patient volunteers.

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Found 106 clinical trials
Cyclosporine in Patients With Moderate COVID-19

Phase 1 safety study to determine the tolerability, clinical effects, and changes in laboratory parameters of short course oral or IV cyclosporine (CSA) administration in patients with COVID-19 disease requiring oxygen supplementation but not requiring ventilator support.

SARS
cyclosporin a
estimated creatinine clearance
acute respiratory syndrome (sars)
oxygen supplementation
University of Pennsylvania
 (8.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Open-label Study to Determine the Maximum Tolerated Dose of DSG3-CAART in Mucosal-dominant PV Patients (mPV)

Mucosal-dominant pemphigus vulgaris (mPV) is a B-cell mediated autoimmune disorder in which painful blisters are formed on the mucosal membrane, including the mouth, nose, throat, eyelids, anus, and genitals. This phase 1 study is being conducted to find the maximum tolerated dose and optimal fractionated infusion schedule of an investigational …

University of Pennsylvania
 (8.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of CPI-006 as Immunotherapy for Hospitalized COVID-19 Patients

This Phase 1 single-dose, dose-escalation study is an open label trial evaluating the safety of CPI-006, a humanized monoclonal antibody targeting the CD73 cell-surface ectonucleotidase, as immunotherapy for stable hospitalized mild or moderately symptomatic COVID-19 patients.

nasopharyngeal swab
SARS
cancer
monoclonal antibodies
nasal swab
Temple University Hospital
 (4.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

hypothermia
life support
cardiac arrest
resuscitation
induced hypothermia
Temple University Hospital
 (4.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
body mass index
cardiovascular disease
tirzepatide
Northeast Endocrine Metabolic Associates
 (6.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

sarcoma
recurrent endometrial cancer
maintenance therapy
measurable disease
cancer therapy
Research Site
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
flortaucipir
mini-mental state examination
florbetapir
alzheimer's disease
Clinical Trial Center, LLC, Psychiatry
 (1.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
PCSK9i in AAA12

Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol

Hospital Test2a
 (8.7 away) Contact site
  • 0 views
  • 21 Nov, 2024
  • 1 location
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

aphasia
progranulin
pick's disease
dementia
University of Pennsylvania
 (8.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +46 other locations
Study of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Evaluate the safety and tolerability of AMG 509 in adult subjects and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

neutrophil count
antiandrogen therapy
serum testosterone
orchiectomy
metastasis
Research Site
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations