Lakewood, Ohio Clinical Trials

A listing of Lakewood, Ohio clinical trials actively recruiting patient volunteers.

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Found 45 clinical trials
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation (TIRO-AF)

This is a single center randomized double blind controlled study of patients (BMI> 30 kg/m2) with obesity and Atrial Fibrillation (AFIB) randomized to Tirzepatide vs. placebo. It is expected that the significant weight loss with Tirzepatide will result in improved control, management, symptom severity, and burden of AFIB at 12 …

Cleveland Clinic
 (9.4 away) Contact site
  • 0 views
  • 31 Jan, 2025
  • 1 location
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away …

stereotactic radiosurgery
renal cell carcinoma
melanoma
relieve pain
compression fracture
Cleveland Clinic Taussig Cancer Center
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

cancer
thoracoscopy
wedge resection
wedge excision
pulmonary resection
Cleveland Clinic
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

The purpose of the study is to test how well patients with advanced solid tumors and ovarian cancer respond to treatment with BAY1895344 in combination with niraparib. In addition researchers want to find for patients the optimal dose of BAY1895344 in combination with niraparib, how the drug is tolerated and …

primary peritoneal carcinoma
ovarian cancer
peritoneal cancer
metastasis
ATR
Cleveland Clinic
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

nitrosoureas
non-hodgkin lymphoma
stem cell transplantation
recurrent melanoma
recurrent osteosarcoma
Cleveland Clinic Foundation
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

cancer
castration-resistant prostate cancer
prostatic neoplasm
testosterone
antiandrogen therapy
Cleveland Clinic
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +21 other locations
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

deficiency
imiglucerase
eliglustat
gaucher disease
Investigational Site Number 840048
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +220 other locations
Mucopolysaccharidosis I (MPS I) Registry

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients …

Investigational Site Number 840048
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +135 other locations
Pompe Disease Registry

The Pompe Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Pompe disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The objectives …

replacement therapy
myozyme
gaa gene
deficiency
glycogen storage disease type ii
Investigational Site Number 840048
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +190 other locations
Fabry Disease Registry & Pregnancy Sub-registry

The Fabry Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Fabry disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The primary …

agalsidase beta
replacement therapy
alpha-galactosidase
fabrazyme
deficiency
Investigational Site Number 840048
 (9.4 away) Contact site
  • 0 views
  • 05 Aug, 2024
  • +136 other locations