Garfield Heights, Ohio Clinical Trials

A listing of Garfield Heights, Ohio clinical trials actively recruiting patient volunteers.

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Found 61 clinical trials
Single- vs. Two-Fraction Spine Stereotactic Radiosurgery for the Treatment of Vertebral Metastases

Spine radiosurgery (SRS) utilizes advanced treatment planning with focused x-rays to deliver one to four high dose treatments to the spine to help relieve pain and/or neurologic symptoms. Spine SRS uses special equipment to position the participant and guide the focused beams toward the area to be treated and away …

x-rays
relieve pain
mri spine
neurologic symptoms
external beam radiation therapy
Cleveland Clinic Taussig Cancer Center
 (6.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

folic acid
thoracic surgery
lung cancer
infrared imaging
wedge excision
Cleveland Clinic
 (6.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

The purpose of the study is to test how well patients with advanced solid tumors and ovarian cancer respond to treatment with BAY1895344 in combination with niraparib. In addition researchers want to find for patients the optimal dose of BAY1895344 in combination with niraparib, how the drug is tolerated and …

niraparib
primary peritoneal carcinoma
measurable disease
peritoneal cancer
metastasis
Cleveland Clinic
 (6.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

erbb1
egf receptors
lymphoma
blood test
measurable disease
University Hospitals Cleveland /ID# 212241
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

radiopharmaceutical
cns involvement
ascites
positron emission tomography
absolute neutrophil count
Cleveland Clinic Foundation
 (6.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
Multicenter Clinical Trial of a Phakic Implantable Collamer Lens (ICL)

This objective of this study is to evaluate the safety, and to collect supportive data on effectiveness of the EVO/EVO+ Visian Implantable Collamer Lens (ICL) in study participants who have a diagnosis of myopia or myopia with astigmatism. Primary study analysis will be evaluated when 300 primary eyes complete 6 …

myopia
astigmatism
severe myopia
Cleveland Eye Clinic
 (6.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +13 other locations
A Study of SGN-B6A in Advanced Solid Tumors

This trial will look at a drug called SGN-B6A to find out whether it is safe for people who have solid tumors. It will study SGN-B6A to find out what its side effects are. A side effect is anything the drug does besides treating cancer. It will also study whether …

squamous cell carcinoma of head and neck
bladder cancer
cervical cancer
measurable disease
small cell lung cancer
Case Western Reserve University / University Hospitals Cleveland Medical Center
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Safety and Effectiveness of the PXL-Platinum 330 System

To evaluate the safety and effectiveness of the PXL Platinum 330 system for performing corneal cross-linking (CXL) for the treatment of ectatic disorders.

radial keratotomy
terrien's marginal degeneration
keratoconus
riboflavin
Cleveland Eye Clinic
 (6.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation (TIRO-AF)

This is a single center randomized double blind controlled study of patients (BMI> 30 kg/m2) with obesity and Atrial Fibrillation (AFIB) randomized to Tirzepatide vs. placebo. It is expected that the significant weight loss with Tirzepatide will result in improved control, management, symptom severity, and burden of AFIB at 12 …

Cleveland Clinic
 (6.0 away) Contact site
  • 0 views
  • 31 Jan, 2025
  • 1 location
Reducing Stroke Risk in African-American Men

The project is a 6-month prospective Randomized Controlled Trial evaluating the effects of TargEted MAnageMent Intervention (TEAM, N=80) vs. wait-list (WL, N=80) control in African American men who have experienced a stroke or TIA within the past 5 years.

stroke
acute stroke
Case Western Reserve University
 (6.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location