Gahanna, Ohio Clinical Trials

A listing of Gahanna, Ohio clinical trials actively recruiting patient volunteers.

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Found 48 clinical trials
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

apolipoprotein e4
mini-mental state examination
mental state examination
alzheimer's disease
Accepts healthy volunteers
Novartis Investigative Site
 (7.4 away) Contact site
  • 32 views
  • 20 Sep, 2024
  • +126 other locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

teriflunomide
pregnancy test urine
multiple sclerosis
brain lesion
contraceptive use
Investigational Site Number 8400010
 (7.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +15 other locations
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis (FREVIVA)  

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the disability progression and the safety up to approximately 51 months administration of study intervention compared to placebo in male and female participants with nrSPMS (aged 18 to 60 years at …

Ohio State University Site Number : 8400009
 (7.9 away)
  • 0 views
  • 04 Mar, 2025
  • +58 other locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

teriflunomide
pregnancy test urine
multiple sclerosis
brain lesion
contraceptive use
Investigational Site Number 8400010
 (7.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow

This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE). Researchers want to see which surgery is more helpful for people with ulnar neuropathy. This research will determine if …

Ohio State University
 (7.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
Open-Label Study With Pimavanserin on Activities of Daily Living in Subjects With Parkinson's Disease Psychosis

To assess the effect of pimavanserin on the activities of daily living in subjects with Parkinson's Disease Psychosis

OrthoNeuro (Optimed)
 (5.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +18 other locations
A Study of Subcutaneous Risankizumab Injection for Pediatric Participants With Moderate to Severe Plaque Psoriasis to Assess Change in Disease Symptoms

Psoriasis is a chronic, systemic, inflammatory disease in which skin cells build up and develop thick, red and white scaly patches on the skin. There is an unmet medical need for effective treatment in pediatric patients and this study is being done to evaluate risankizumab in pediatric participants with moderate …

inflammatory disease
blood tests
risankizumab
systemic therapy
psoriasis
The Ohio State University - Columbus /ID# 217808
 (7.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +8 other locations
A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)

This is a Phase Ib/II study to evaluate the safety and efficacy of autologous T cells engineered with a chimeric antigen receptor (CAR) targeting CD19 in adult patients with relapsed or refractory B cell acute lymphoblastic leukemia (ALL).

Ohio State University Cancer Center
 (7.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +29 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

positron emission tomography
flortaucipir
mini-mental state examination
florbetapir
alzheimer's disease
Ohio State University Medical Center
 (10.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in NRSPMS Secondary Objective: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety and tolerability of SAR442168 …

contraceptive use
secondary progressive multiple sclerosis
chronic progressive multiple sclerosis
multiple sclerosis
Investigational Site Number 8400010
 (7.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +15 other locations