Dayton, Ohio Clinical Trials

A listing of Dayton, Ohio clinical trials actively recruiting patient volunteers.

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Found 31 clinical trials
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

mini-mental state examination
apolipoprotein e4
mental state examination
alzheimer's disease
Accepts healthy volunteers
Novartis Investigative Site
 (9.1 away) Contact site
  • 32 views
  • 20 Sep, 2024
  • +126 other locations
Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

The primary objective of this study is to demonstrate the non-inferiority of the vaccine seroresponse to meningococcal serogroups A, C, Y, and W following administration of 2 doses of MenACYW conjugate vaccine compared to 2 doses of MENVEO when given concomitantly with routine pediatric vaccines to infants and toddlers 6 …

Investigational Site Number 8400008
 (5.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +47 other locations
A Trial to Evaluate the Efficacy and Safety of RSVpreF in Infants Born to Women Vaccinated During Pregnancy.

This randomized, double-blinded, placebo-controlled Phase 3 study is designed to evaluate the efficacy and safety of maternal immunization with RSVpreF against medically attended lower respiratory tract illness (MA-LRTI) in infants.

vaccination
hepatitis b
antigen test
syphilis test
lower respiratory tract infection
Schear Family Practice
 (2.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +155 other locations
Open-Label Study With Pimavanserin on Activities of Daily Living in Subjects With Parkinson's Disease Psychosis

To assess the effect of pimavanserin on the activities of daily living in subjects with Parkinson's Disease Psychosis

Neurology Diagnostics, Inc.
 (9.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +18 other locations
Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) Before and During Treatment With Ocrelizumab

This is an open-label, multicenter study that includes a main study for all participants enrolled and an optional cerebrospinal fluid (CSF) sub-study. Self-identified African American (AA) and Hispanic or Latin American (HA) participants with a diagnosis of relapsing multiple sclerosis (RMS) will be enrolled. The treating neurologist must make an …

Neurology Specialists, Inc
 (1.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +30 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

cancer treatment
carcinosarcoma
immunomodulator
paclitaxel
carboplatin
Research Site
 (9.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

mini-mental state examination
florbetapir
flortaucipir
positron emission tomography
alzheimer's disease
University of Cincinnati Health Neurology
 (1.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

aubagio
serum pregnancy test
multiple sclerosis
brain lesion
teriflunomide
Investigational Site Number 8400081
 (9.1 away) Contact site
  • 0 views
  • 09 Sep, 2025
  • +24 other locations
Study on a High-Dose Quadrivalent Influenza Vaccine Compared With Standard-Dose Quadrivalent Influenza Vaccine in Children 6 Months Through 35 Months of Age

The primary objective of the study is to compare the clinical efficacy of high-dose quadrivalent influenza vaccine (QIV-HD) to standard-dose quadrivalent influenza vaccine (QIV-SD) in participants 6 months through 35 months of age for the prevention of laboratory-confirmed influenza illness caused by any influenza A or B type. The secondary …

flu symptoms
vaccination
quadrivalent inactivated influenza vaccine
influenza
hemagglutination inhibition
Investigational Site Number 8400027
 (7.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
Follow-up Study of Growth Safety and Efficacy of an Infant Formula for Healthy Term Infants

The purpose of this two-month follow-up study is to continue to follow growth, safety, and other health outcomes of infants fed a new infant formula for term infants or comparator formula. A reference group of human milk-fed infants will also be followed. This study is designed in accordance with Good …

Schear Family Practice
 (2.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +24 other locations