Columbus, Ohio Clinical Trials

A listing of Columbus, Ohio clinical trials actively recruiting patient volunteers.

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Found 48 clinical trials
Maximal Usage Pharmacokinetics and Safety of ARQ-151 in Adolescents and Adults With Chronic Plaque Psoriasis

This is a phase 1, open label, single arm study in which ARQ-151 cream 0.3% is applied QD for 2 weeks to adolescent subjects with chronic plaque psoriasis involving at least 10% body surface area (BSA) and adult subjects with chronic plaque psoriasis involving at least 20% BSA (excluding scalp). …

psoriasis
electrocardiogram
serum pregnancy test
psoriasis vulgaris
12 lead electrocardiogram
Arcutis Clinical Site 01
 (7.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in NRSPMS Secondary Objective: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety and tolerability of SAR442168 …

multiple sclerosis
contraceptive use
chronic progressive multiple sclerosis
secondary progressive multiple sclerosis
Investigational Site Number 8400010
 (4.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +15 other locations
Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168 (PERSEUS)

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary Objectives: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety …

oligoclonal bands
Investigational Site Number 8400147
 (2.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +14 other locations
Accelerating Colorectal Cancer Screening Through Implementation Science in Appalachia

This project aims to implement a multi-level group randomized trial, delayed intervention that includes components targeting clinics, providers, patients, and the community to increase colorectal cancer (CRC) screening, follow-up, and referral-to-care among patients age 50-74 in 12 counties in Appalachian Kentucky and Ohio. The 12 counties will be assigned to …

colorectal cancer screening
colorectal cancer
cancer screening
screening for colorectal cancer
Ohio State University
 (6.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

alzheimer's disease
flortaucipir
florbetapir
positron emission tomography
mini-mental state examination
Ohio State University Medical Center
 (6.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts

A single arm clinical trial evaluating the safety and efficacy of the second generation TEVG as vascular conduits for extracardiac total cavopulmonary connection.

total cavopulmonary connection
Nationwide Children's Hospital
 (9.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Test trial v7.2 (May 13) - Test 1 (Acro - Test 1)

Test trial v7.2 (May 13) - Test 1

The Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute- Site Number : 8401009
 (6.2 away) Contact site
  • 0 views
  • 13 May, 2025
  • +2 other locations
A Study to Assess Pulsed Inhaled Nitric Oxide vs Placebo in Subjects With Mild or Moderate COVID-19

A randomized, double-blind, placebo-controlled study to assess the efficacy and safety of pulsed inhaled iNO compared to placebo in subjects with COVID-19.

SARS
ct scan
treatment regimen
covid-19
x-rays
The Ohio State University Wexner Medical Center
 (6.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +13 other locations
ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease  

The purpose of this study is to evaluate the safety and efficacy of the ExAblate Model 4000 Type 2.0 System as a tool to disrupt the blood-brain barrier (BBB) in patients with probable Alzheimer's Disease (AD).

alzheimer's disease
The Ohio State University -Wexner Medical Center
 (6.9 away)
  • 0 views
  • 09 May, 2025
  • +2 other locations
Black Raspberry Nectar for the Prevention of Lung Cancer BE WELL Study

This trial studies how well black raspberry nectar works in changing the gut microbiome and in reducing inflammatory processes that may lead to lung cancer. Studying the effects of black raspberry beverage on inflammation may help doctors find strategies to reduce the risk of developing lung cancer.

cancer
carcinoma
lung carcinoma
vitamins
lung cancer
Ohio State University Comprehensive Cancer Center
 (6.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location