Yonkers, New York Clinical Trials

A listing of Yonkers, New York clinical trials actively recruiting patient volunteers.

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Found 67 clinical trials
Study of Lademirsen (SAR339375) in Patients With Alport Syndrome  

Primary Objectives: To assess the efficacy of lademirsen (SAR339375) in reducing the decline in renal function To assess the safety and tolerability of lademirsen (SAR339375) in subjects with Alport syndrome Secondary Objectives: To assess plasma pharmacokinetic (PK) parameters of the parent compound and its metabolites To assess the potential formation …

Columbia University Medical Center_Investigational Site Number :8400004
 (8.3 away)
  • 0 views
  • 01 Dec, 2025
  • +19 other locations
A Study to Evaluate the Efficacy and Safety of Frexalimab, SAR442970, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease (RESULT)

This is a parallel, Phase 2a, double-blind, 6-arm study for the treatment of primary focal segmental glomerulosclerosis (FSGS) or primary minimal change disease (MCD).The purpose of this study is to measure the change in proteinuria and its impact on the rates of remission of nephrotic syndrome with frexalimab, SAR442970, or …

Investigational Site Number : 8400001
 (8.3 away) Contact site
  • 0 views
  • 20 Jun, 2025
  • +24 other locations
Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission - Josh McVoy  

The study will explore the effects of early intensive antiretroviral therapy (ART) with or without a broadly neutralizing antibody (bNAb) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among infants living with HIV.

12001, Malawi Clinical Research Site
 (6.6 away)
  • 0 views
  • 24 Apr, 2026
  • +1 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

aphasia
progranulin
pick's disease
dementia
Irving Institute for Clinical and Translational Research
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +46 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

treatment regimen
lasmiditan
migraine
headache
ly573144
Care Access Research - Bronx
 (8.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +162 other locations
2019-06 TRISCEND Study

Early feasibility study to assess safety and performance of the Edwards EVOQUE Tricuspid Valve Replacement System

medical therapy
tricuspid valve replacement
Columbia University Irving Medical Center / NYPH
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Dynamically Tailored Behavioral Interventions in Diabetes

In this project, the investigators will evaluate the efficacy of a novel approach to personalizing behavioral interventions for self-management of type 2 diabetes (T2DM) to individuals' behavioral and glycemic profiles discovered using computational learning and self-monitoring data. This study is a two-arm randomized controlled trial with n=280 participants recruited from …

self monitoring
behavior modification
Columbia University Irving Medical Center
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

The blood brain barrier (BBB) prevents some drugs from successfully reaching the target source. Convection-Enhanced Delivery (CED) is a method of direct infusion of drugs under controlled pressure to the tumor that may reduce systemic side effects of drugs in the patient. The purpose of this Phase I study is …

neutrophil count
karnofsky performance status
pediatric
epilepsy
anticonvulsants
Columbia University Irving Medical Center
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

HER2
pembrolizumab
exhausted
metastasis
solid tumor
Bolt Investigative Site
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

neutrophil count
iobenguane
recurrent osteosarcoma
solid tumor
match treatment
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations