Palisades Park, New Jersey Clinical Trials

A listing of Palisades Park, New Jersey clinical trials actively recruiting patient volunteers.

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Found 422 clinical trials
CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

The blood brain barrier (BBB) prevents some drugs from successfully reaching the target source. Convection-Enhanced Delivery (CED) is a method of direct infusion of drugs under controlled pressure to the tumor that may reduce systemic side effects of drugs in the patient. The purpose of this Phase I study is …

glioma
neutrophil count
thromboplastin
pediatric
dipg
Columbia University Irving Medical Center
 (2.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment

A Phase1/2a Study of Rigosertib plus Nivolumab in Stage IV Lung Adenocarcinoma Patients with KRAS Mutation who Progressed on First-Line Treatment

nivolumab
lung adenocarcinoma
tubal ligation
hysterectomy
lung cancer
Icahn School of Medicine at Mount Sinai
 (4.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

The purpose of the study is to test how well patients with advanced solid tumors and ovarian cancer respond to treatment with BAY1895344 in combination with niraparib. In addition researchers want to find for patients the optimal dose of BAY1895344 in combination with niraparib, how the drug is tolerated and …

metastasis
neutrophil count
ovarian cancer
prostate cancer
ATR
Memorial Sloan-Kettering Cancer Center
 (5.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

solid tumor
pembrolizumab
metastasis
measurable disease
gene amplification
Bolt Investigative Site
 (2.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

pembrolizumab
stage iv non-small cell lung cancer
lymphoma
egf receptors
venetoclax
Hackensack Univ Med Ctr /ID# 216484
 (3.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
RCT of Ovarian Function Following Intraovarian Injection of PRP

Consenting women with evidence of poor ovarian reserve will be randomly assigned to treatment with either Platelet Rich Plasma (PRP) or Platelet Poor Plasma (PPP).

Center for Human Reproduction
 (5.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Heart Transplantation Using Normothermic Regional Perfusion Donation After Circulatory Death

Normothermic regional perfusion (NRP) utilizes Extracorporeal Membrane Oxygenation (ECMO) or cardiopulmonary bypass to reperfuse the heart and other organs in situ after isolation and ligation of the cerebral vessels. In situ resuscitation of the heart has the added advantage of allowing full hemodynamic and echocardiographic assessment of the donor heart …

heart transplantation
NYU Langone Health
 (6.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs

The investigators are doing this study to find out whether lowering the dose of postoperative radiation therapy and targeting a smaller area of tissue for treatment is as effective as the standard dose and volume of radiation therapy to control soft tissue sarcoma after surgery. They also want to find …

sarcoma
sarcoma of the extremity
soft tissue sarcoma
primary tumor
serum pregnancy test
Memorial Sloan Kettering Cancer Center
 (5.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

hodgkin's disease
cns tumor
HRAS
pleural effusion
anti-cancer agents
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
 (2.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

glioma
neurofibroma
neutrophil count
measurable disease
nf2 gene
Memorial Sloan Kettering Cancer Center (Site 210)
 (5.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +16 other locations