Oradell, New Jersey Clinical Trials

A listing of Oradell, New Jersey clinical trials actively recruiting patient volunteers.

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Found 80 clinical trials
CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas

The blood brain barrier (BBB) prevents some drugs from successfully reaching the target source. Convection-Enhanced Delivery (CED) is a method of direct infusion of drugs under controlled pressure to the tumor that may reduce systemic side effects of drugs in the patient. The purpose of this Phase I study is …

acute infection
epilepsy
karnofsky performance status
anesthesia
side effects of drugs
Columbia University Irving Medical Center
 (9.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A First-in-human Study Using BDC-1001 in Advanced and HER2-Expressing Solid Tumors

A first-in-human study using BDC-1001 in HER2 expressing advanced malignancies

advanced malignant solid tumor
solid tumor
exhausted
measurable disease
pembrolizumab
Bolt Investigative Site
 (9.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

stage iv non-small cell lung cancer
drug test
measurable disease
growth factor
pembrolizumab
Hackensack Univ Med Ctr /ID# 216484
 (4.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
Dose Reduction of Postoperative Radiation for Soft Tissue Sarcoma of the Arms and Legs

The investigators are doing this study to find out whether lowering the dose of postoperative radiation therapy and targeting a smaller area of tissue for treatment is as effective as the standard dose and volume of radiation therapy to control soft tissue sarcoma after surgery. They also want to find …

serum pregnancy test
primary tumor
sarcoma
soft tissue sarcoma
sarcoma of the extremity
Memorial Sloan Kettering Bergen (All protocol activities)
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

recurrent childhood medulloblastoma
measurable disease
nervous system
positron emission tomography
solid tumors
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center
 (9.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
Targeted Fortification of Donor Breast Milk in Preterm Infants

This study is a randomized controlled trial comparing standard fortification of donor breast milk to targeted fortification of donor breast milk in preterm infants. The purpose of the study is to determine if there is a benefit to target fortifying donor breast milk in the preterm population. The investigators hypothesize …

Columbia University Medical Center/ New York - Presbyterian
 (9.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

This research study is studying a new drug, NC410, as a possible treatment for advanced or metastatic solid tumors.

serum pregnancy test
oophorectomy
measurable disease
solid tumour
metastasis
John Theurer Cancer Center at Hackensack University Medical Center
 (4.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of Enasidenib in People With Clonal Cytopenia of Undetermined Significance

Study researchers think that a drug called enasidenib may help people with clonal cytopenia of undetermined significance (CCUS) because the drug blocks the mutated IDH2 protein, which may improve blood cell counts. The purpose of this study is to find out whether enasidenib is a safe and effective treatment for …

Memorial Sloan Kettering Bergen (Limited Protocol Activities)
 (7.0 away) Contact site
  • 0 views
  • 02 Dec, 2024
  • +6 other locations
Test Food4GutMarKIT - Evaluation of a Tailored Personalized Food Concept for a Healthy Gut Microbiota and Validation of Biomarkers for Monitoring of Its Effects  

The overall test test test test aim in this "proof-of-concept" study is to evaluate if a diet concept, based on foods that have individually been reported to beneficially affect gut microbiota in fact has an effect on gut microbiota composition and activity among healthy and obese subjects and whether the …

Accepts healthy volunteers
Columbia University Medical Center_Investigational Site Number :8400004
 (9.0 away)
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Meal Response, Protein, and PCOS  

Polycystic ovary syndrome (PCOS) is a common endocrine disorder characterized by insulin resistance, hyperandrogenism, and reproductive dysfunction. Dietary strategies that improve postprandial insulin and glucose responses are central to managing metabolic symptoms in PCOS. Protein-rich meals can attenuate postprandial glycemia and enhance satiety, but the effects may vary by protein …

Columbia University Medical Center_Investigational Site Number :8400004
 (9.0 away)
  • 0 views
  • 06 Dec, 2025
  • +3 other locations