Hackensack, New Jersey Clinical Trials

A listing of Hackensack, New Jersey clinical trials actively recruiting patient volunteers.

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Found 258 clinical trials
Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Subjects with Neurofibromatosis Type 2 (NF2) and progressive vestibular schwannoma (VS) will be treated with crizotinib administered orally. Crizotinib will be taken continuously until disease progression or unacceptable toxicity, in continuous treatment cycles of 28 days each, for a maximum of 12 cycles.

cataract
measurable disease
multiple meningiomas
glioma
schwartz
Memorial Sloan Kettering Cancer Center (Site 210)
 (9.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +16 other locations
Targeted Fortification of Donor Breast Milk in Preterm Infants

This study is a randomized controlled trial comparing standard fortification of donor breast milk to targeted fortification of donor breast milk in preterm infants. The purpose of the study is to determine if there is a benefit to target fortifying donor breast milk in the preterm population. The investigators hypothesize …

Columbia University Medical Center/ New York - Presbyterian
 (6.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

kras
solid tumour
metastatic malignant solid tumor
ki-ras
solid tumor
Memorial Sloan Kettering Cancer Center
 (9.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +7 other locations
Study to Evaluate the Safety Tolerability Pharmacokinetics and Pharmacodynamics of CC-94676 in Subjects With Metastatic Castration-Resistant Prostate Cancer

This is a first in human study to assess the safety, tolerability, PK, PD and preliminary efficacy of CC-94676 in men with progressive metastatic castration-resistant prostate cancer.

castration-resistant prostate cancer
bilateral orchidectomy
apalutamide
adenocarcinoma of prostate
gonadorelin
Memorial Sloan-Kettering Cancer Center
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
A Safety and Tolerability Study of NC410 in Subjects With Advanced or Metastatic Solid Tumors

This research study is studying a new drug, NC410, as a possible treatment for advanced or metastatic solid tumors.

systemic therapy
measurable disease
bilateral oophorectomy
metastasis
serum pregnancy test
John Theurer Cancer Center at Hackensack University Medical Center
 (0.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
First-in-human Single Agent Study of SAR442085 in Relapsed or Refractory Multiple Myeloma

Primary Objectives: Dose Escalation Part A: To determine the maximum tolerated dose (MTD) of SAR442085 administered as a single agent in patients with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose (RP2D) for the subsequent Expansion Part B Dose Expansion Part B: To assess the …

daratumumab
line of therapy
ixazomib
bortezomib
lenalidomide
Investigational Site Number 8400001
 (8.6 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • +7 other locations
A Study of Enasidenib in People With Clonal Cytopenia of Undetermined Significance

Study researchers think that a drug called enasidenib may help people with clonal cytopenia of undetermined significance (CCUS) because the drug blocks the mutated IDH2 protein, which may improve blood cell counts. The purpose of this study is to find out whether enasidenib is a safe and effective treatment for …

Memorial Sloan Kettering Cancer Center (All Protocol Activities)
 (9.7 away) Contact site
  • 0 views
  • 02 Dec, 2024
  • +6 other locations
Test Food4GutMarKIT - Evaluation of a Tailored Personalized Food Concept for a Healthy Gut Microbiota and Validation of Biomarkers for Monitoring of Its Effects  

The overall test test test test aim in this "proof-of-concept" study is to evaluate if a diet concept, based on foods that have individually been reported to beneficially affect gut microbiota in fact has an effect on gut microbiota composition and activity among healthy and obese subjects and whether the …

Accepts healthy volunteers
Columbia University Medical Center_Investigational Site Number :8400004
 (6.4 away)
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Spacer Graft Study (abc)

To determine which of three types of spacer grafts (hard palate vs autologous ear cartilage vs Enduragen) are the most effective in lower eyelid retraction repair outcomes as measured by MRD2 (margin to reflex distance 2)

Accepts healthy volunteers
Montefiore Medical Center
 (9.4 away) Contact site
  • 0 views
  • 14 May, 2025
  • 1 location
None

Memorial Sloan Kettering Cancer Center
 (9.7 away) Contact site
  • 0 views
  • 19 May, 2025
  • +12 other locations