Houston, Louisiana Clinical Trials

A listing of Houston, Louisiana clinical trials actively recruiting patient volunteers.

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Found 93 clinical trials
A Trial to Evaluate the Efficacy and Safety of RSVpreF in Infants Born to Women Vaccinated During Pregnancy.

This randomized, double-blinded, placebo-controlled Phase 3 study is designed to evaluate the efficacy and safety of maternal immunization with RSVpreF against medically attended lower respiratory tract illness (MA-LRTI) in infants.

vaccination
hepatitis b
antigen test
lower respiratory tract infection
prenatal
The University of Texas Medical School at Houston
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +155 other locations
A Study To Investigate The Safety Tolerability Pharmacokinetics And Pharmacodynamics Of RO7248824 In Participants With Angelman Syndrome

This is a Phase I, multicenter, non-randomized, adaptive, open label, multiple ascending, intra-participant, dose-escalation study using IT administration to investigate the safety, tolerability, PK and PD of RO7248824 in participants with AS. Two linked sets of dose escalation cohorts are planned based on two different age groups, namely participants with …

Baylor College of Med; Texas Child Hosp; Pediactric Dept
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
Aprepitant Injectable Emulsion in Patients With COVID-19 (GUARDS-1)

The study will evaluate the efficacy and safety of aprepitant injectable emulsion added to standard of care for hospitalized patients with COVID-19.

oximetry
SARS
PCR test
covid-19
mechanical ventilation
Memorial Hermann - Memorial City Medical Center
 (8.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
Efficacy of Buprenorphine for Treatment of Acute Pain  

The purpose of this study is to determine whether sublingual buprenorphine is effective in the treatment of acute pain in adult patients with extremity bone fractures

buprenorphine
morphine
acute pain
C Site 3
 (4.1 away)
  • 0 views
  • 20 Sep, 2024
  • +12 other locations
Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen

Patients eligible for this study have a type of blood cancer Acute Myeloid Leukemia (AML) which has come back or has not gone away after treatment. The body has different ways of fighting disease and infection, and this research study combines two different ways of fighting cancer with antibodies and …

hematologic malignancy
immunohistochemistry
aptt
allogeneic hematopoietic stem cell transplant
lymphoma
Texas Children's Hospital
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Venetoclax SL-401 and Chemotherapy for the Treatment of Blastic Plasmacytoid Dendritic Cell Neoplasm

This phase II trial studies how well venetoclax, SL-401, and chemotherapy works in treating patients with blastic plasmacytoid dendritic cell neoplasm. Venetoclax may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. SL-401 is a recombinant protein consisting of IL-3 linked to a …

hydroxyurea
ejection fraction
gilbert's syndrome
oral contraceptives
treatment regimen
M D Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Caterpillar Arterial Embolization Device Post-Market Study

The primary objective of this study is to evaluate the performance and safety of the Caterpillar Arterial Embolization Device when used for arterial embolization in the peripheral vasculature in a real world, on-label application.

University of Texas Health Science Center at Houston
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +11 other locations
An Extension Study MRI/US Fusion Imaging and Biopsy in Combination With Nanoparticle Directed Focal Therapy for Ablation of Prostate Tissue

To determine the efficacy of using MRI/US fusion imaging technology to direct focal ablation of prostate tissue using nanoparticle-directed laser irradiation.

University of Texas Medical School at Houston
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Safety and Efficacy of IMC-F106C as a Single Agent and in Combination With Checkpoint Inhibitors

IMC-F106C is an immune-mobilizing T cell receptor against cancer (ImmTAC ) designed for the treatment of cancers positive for the tumor-associated antigen PRAME. This is a first-in-human trial designed to evaluate the safety and efficacy of IMC-F106C in adult patients who have the appropriate HLA-A2 tissue marker and whose cancer …

MD Anderson Cancer Center
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease

This is a non-randomized, open-label, multi-site, single-dose, Phase 3 study in approximately 35 adults and pediatric subjects 2 and 50 years of age with sickle cell disease (SCD). The study will evaluate hematopoietic stem cell (HSC) transplantation (HSCT) with LentiGlobin BB305 Drug Product for SCD.

priapism
pediatric
gene therapy
karnofsky performance status
analgesia
Baylor College of Medicine/Texas Children's Hospital
 (4.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations