Westwood, Kansas Clinical Trials

A listing of Westwood, Kansas clinical trials actively recruiting patient volunteers.

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Found 51 clinical trials
SPEARHEAD 2 Study in Subjects With Recurrent or Metastatic Head and Neck Cancer

This is a study to investigate the efficacy and safety of ADP-A2M4 in combination with pembrolizumab in HLA-A*02 eligible and MAGE-A4 positive subjects with recurrent or metastatic Head and Neck cancer.

cyclophosphamide
monoclonal antibody therapy
monoclonal antibodies
pd-l1
ejection fraction
University of Kansas Medical Center
 (1.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)

This is a Phase Ib/II study to evaluate the safety and efficacy of autologous T cells engineered with a chimeric antigen receptor (CAR) targeting CD19 in adult patients with relapsed or refractory B cell acute lymphoblastic leukemia (ALL).

University of Kansas
 (1.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +29 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
body mass index
tirzepatide
cardiovascular disease
University of Kansas Medical Center
 (1.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

antiretroviral therapy
monoclonal antibody therapy
sarcoma
non-small cell lung cancer
stage ii lung squamous cell carcinoma ajcc v7
Saint Luke's Hospital of Kansas City
 (1.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +358 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

dementia
pick's disease
progranulin
aphasia
University of Kansas Alzheimer's Disease Center
 (1.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +46 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

headache
ly573144
treatment regimen
migraine
preventive medication
Children Mercy Pediatric Clinical Research Unit
 (2.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +162 other locations
KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated Nonsquamous NSCLC

This is a Phase 2, randomized, multicenter, double-blind study of the glutaminase inhibitor telaglenastat with standard-of-care pembrolizumab and chemotherapy versus placebo with standard-of-care pembrolizumab and chemotherapy for first line treatment of metastatic disease in patients with KEAP1/NRF2-mutated, stage IV, nonsquamous, non-small cell lung cancer (NSCLC). The study primary endpoints are …

stage iv non-small cell lung cancer
EGFR
liquid biopsy
adjuvant therapy
pemetrexed
HCA Midwest Health - Menorah Medical Center (SCRI)
 (4.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +27 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

epidermal growth factor
drug test
small cell lung cancer
growth factor
metastatic nsclc
Univ Kansas Med Ctr /ID# 216897
 (1.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

recurrent childhood medulloblastoma
blood count
melanoma
positron emission tomography
cns tumor
Children's Mercy Hospitals and Clinics
 (2.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
Multicenter Clinical Trial of a Phakic Implantable Collamer Lens (ICL)

This objective of this study is to evaluate the safety, and to collect supportive data on effectiveness of the EVO/EVO+ Visian Implantable Collamer Lens (ICL) in study participants who have a diagnosis of myopia or myopia with astigmatism. Primary study analysis will be evaluated when 300 primary eyes complete 6 …

severe myopia
astigmatism
myopia
Durrie Vision
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +13 other locations