Lenexa, Kansas Clinical Trials

A listing of Lenexa, Kansas clinical trials actively recruiting patient volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 42 clinical trials
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

alzheimer's disease
mental state examination
apolipoprotein e4
mini-mental state examination
Accepts healthy volunteers
University of Kansas Alzheimer's Disease Center
 (7.2 away) Contact site
  • 32 views
  • 20 Sep, 2024
  • +126 other locations
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients

Primary Objective: To determine the effect of venglustat on the rate of total kidney volume (TKV) growth (Stage and estimated glomerular filtration rate (eGFR) decline in patients at risk of rapidly progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD) (Stage 2). Secondary Objectives: To determine the effect of venglustat on the …

human chorionic gonadotropin
antihypertensive therapy
urine osmolality
chronic kidney disease
polycystic kidney disease
Investigational Site Number 8400003
 (9.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +80 other locations
Phase 2 Study of SAR439859 Versus Physician's Choice in Locally Advanced or Metastatic ER-positive Breast Cancer (AMEERA-3)

Primary Objective: To determine whether SAR439859 per os improves progression free survival (PFS) when compared with a endocrine monotherapy of the choice of the physician, in participants with metastatic or locally advanced breast cancer. Secondary Objectives: To compare the overall survival in the 2 treatment arms To assess the objective …

cancer
cancer metastatic
immunological adjuvant
estrogen
breast cancer
Investigational Site Number 8400027
 (7.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +130 other locations
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis (FREVIVA)  

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the disability progression and the safety up to approximately 51 months administration of study intervention compared to placebo in male and female participants with nrSPMS (aged 18 to 60 years at …

College Park Family Care Center Site Number : 8400032
 (2.9 away)
  • 0 views
  • 04 Mar, 2025
  • +58 other locations
A Study of Ad26.COV2.S in Adults

The purpose of the study is to assess the safety, reactogenicity, and immunogenicity of Ad26.COV2.S at 2 dose levels, administered intramuscularly (IM) as a single-dose or 2-dose schedule, with a single booster vaccination administered in one cohort, in healthy adults aged greater than or equal to 18 to less than …

vaccine administration
vaccination
booster immunization
Johnson County Clin-Trials
 (2.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
Caterpillar Arterial Embolization Device Post-Market Study

The primary objective of this study is to evaluate the performance and safety of the Caterpillar Arterial Embolization Device when used for arterial embolization in the peripheral vasculature in a real world, on-label application.

University of Kansas Medical Center Research Institute
 (9.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +11 other locations
SPEARHEAD 2 Study in Subjects With Recurrent or Metastatic Head and Neck Cancer

This is a study to investigate the efficacy and safety of ADP-A2M4 in combination with pembrolizumab in HLA-A*02 eligible and MAGE-A4 positive subjects with recurrent or metastatic Head and Neck cancer.

cancer
fludarabine
head and neck cancer
recurrent disease
pd-l1
University of Kansas Medical Center
 (9.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)

This is a Phase Ib/II study to evaluate the safety and efficacy of autologous T cells engineered with a chimeric antigen receptor (CAR) targeting CD19 in adult patients with relapsed or refractory B cell acute lymphoblastic leukemia (ALL).

University of Kansas
 (9.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +29 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
cardiovascular disease
body mass index
tirzepatide
University of Kansas Medical Center
 (9.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

This phase III ALCHEMIST trial compares the addition of pembrolizumab to usual chemotherapy versus usual chemotherapy for the treatment of stage IB, II, or IIIA non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the …

pd-l1
HIV Infection
cisplatin
immunohistochemistry
carboplatin
Saint Luke's South Hospital
 (4.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +358 other locations