Winter Park, Florida Clinical Trials

A listing of Winter Park, Florida clinical trials actively recruiting patient volunteers.

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Found 43 clinical trials
Study of Single-dose DS-3201b in Participants With Hepatic Impairment

This is a Phase 1, open-label, parallel design, single-dose pharmacokinetic (PK) study to assess the safety, tolerability, and PK of a single dose of 50 mg of DS-3201b in participants with normal and impaired hepatic function.

vasectomy
moderate hepatic impairment
hormonal contraception
gilbert's syndrome
oral contraceptives
Orlando Clinical Research Center
 (9.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Evaluation of the Integrated Radio Frequency Denervation System to Improve Glycemic Control in Type 2 Diabetic Subjects

The objective of this early feasibility study is to evaluate the safety and performance of intravascular hepatic denervation using the Metavention Integrated Radio Frequency Denervation System (iRF System) to improve glycemic control in type 2 diabetes subjects.

hypertension medication
fatty liver
nash
hypertension
liver disease
AdventHealth Translational Research Institute
 (3.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
Open-Label Study With Pimavanserin on Activities of Daily Living in Subjects With Parkinson's Disease Psychosis

To assess the effect of pimavanserin on the activities of daily living in subjects with Parkinson's Disease Psychosis

Neurology Associates, P.A.
 (2.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +18 other locations
Evaluation of the Efficacy and Safety of VX-864 in Subjects With the PiZZ Genotype

This study will evaluate the efficacy, safety and pharmacokinetics (PK) of VX-864 in PiZZ subjects.

Central Florida Pulmonary
 (3.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

contraceptive use
serum pregnancy test
urine test
pregnancy test urine
teriflunomide
Investigational Site Number 8400004
 (2.1 away) Contact site
  • 0 views
  • 09 Sep, 2025
  • +24 other locations
Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168 (PERSEUS)

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary Objectives: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety …

oligoclonal bands
Investigational Site Number 8400004
 (2.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +14 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
cardiovascular disease
tirzepatide
body mass index
Orlando Heart & Vascular Institute, LLC
 (5.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

alzheimer's disease
positron emission tomography
mini-mental state examination
flortaucipir
florbetapir
Compass Research
 (6.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

treatment regimen
lasmiditan
migraine
ly573144
preventive medication
Pediatric Neurology P.A.
 (0.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +162 other locations
A Study of LY3372993 in Participants With Alzheimer's Disease (AD)

The main purpose of this study is to evaluate the safety and tolerability of LY3372993 in participants with AD. The study will also investigate how much LY3372993 gets into the bloodstream and will test the effects of LY3372993. Participation could last up to about 54 weeks and may include up …

mild cognitive impairment
alzheimer's disease
cognitive impairment
mental state examination
mini-mental state examination
BioClinica Inc
 (6.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations