Tampa, Florida Clinical Trials

A listing of Tampa, Florida clinical trials actively recruiting patient volunteers.

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Found 65 clinical trials
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

carcinoma
measurable disease
immunomodulator
carboplatin paclitaxel
platinum-based chemotherapy
Research Site
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
mini-mental state examination
positron emission tomography
flortaucipir
alzheimer's disease
Axiom Research
 (5.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in NRSPMS Secondary Objective: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety and tolerability of SAR442168 …

multiple sclerosis
chronic progressive multiple sclerosis
secondary progressive multiple sclerosis
contraceptive use
Investigational Site Number 8400001
 (5.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +15 other locations
Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168 (PERSEUS)

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary Objectives: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety …

oligoclonal bands
Investigational Site Number 8400006
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +14 other locations
Long-term Safety and Efficacy Study of Fitusiran in Patients With Hemophilia A or B With or Without Inhibitory Antibodies to Factor VIII or IX

Primary Objective: To characterize the long-term safety and tolerability of fitusiran Secondary Objectives: To characterize the long-term efficacy of fitusiran as assessed by the frequency of: Bleeding episodes Spontaneous bleeding episodes Target joint bleeding episodes To characterize the effects of fitusiran on health-related quality of life (HRQOL) measures in participants …

antihemophilic factor
haemophilia a
hemophilia
hemarthrosis
fitusiran
Investigational Site Number 8400002
 (5.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +43 other locations
Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in NRSPMS Secondary Objective: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonsnce imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety and tolerability of SAR442168 …

chronic progressive multiple sclerosis
multiple sclerosis
contraceptive use
Investigational Site Number 8400006
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

headache
ly573144
migraine
preventive medication
lasmiditan
ForCare Clinical Research
 (9.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +162 other locations
AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With BAN2401 in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

The primary purpose of this study is to determine whether treatment with BAN2401 is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Trial) and to determine whether treatment with BAN2401 is superior to placebo in reducing brain …

University of South Florida - Health Byrd Alzheimer Institute
 (9.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
Microbiome and Rectal Cancer

The purpose of our study is to determine if an association exists between the microbiome of those with rectal adenocarcinoma who are complete pathologic responders and those who have a partial or no response to neoadjuvant therapy.

adenocarcinoma
cancer
neoadjuvant therapy
chemoradiotherapy
rectal carcinoma
Tampa General Hospital
 (7.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +2 other locations
An Efficacy and Safety Study of Ravulizumab in ALS Participants

The purpose of the study is to assess the efficacy and safety of ravulizumab for the treatment of adult participants with ALS.

riluzole
ravulizumab
edaravone
vaccination
University of South Florida
 (9.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations