Gainesville, Florida Clinical Trials

A listing of Gainesville, Florida clinical trials actively recruiting patient volunteers.

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Found 37 clinical trials
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In this prospective cohort study, 250 patients with suspected or known CAD and at least one intermediate coronary lesion (50-70% stenosis) who had a NiFFR value greater than 0.80 underwent coronary computed tomography angiography (CCTA) with NiFFR assessment. Patients were followed for one year to monitor for MACE

Online studies
  • 0 views
  • 28 Aug, 2025
  • Online study
Shweta - Protein and Polycystic Ovary Syndrome (PCOS)  

Polycystic ovary syndrome (PCOS) is a significant public health problem and is one of the most common hormonal disturbances affecting women of reproductive age. Women with PCOS are often insulin resistant, increasing their risk for cardiometabolic health problems (e.g., type 2 diabetes, heart disease, high blood pressure, sleep apnea, anxiety, …

Accepts healthy volunteers
Online studies
  • 0 views
  • 24 Apr, 2026
  • Online study
Social & QoL Behaviors in Parkinson's Disease

Adults with Parkinson's Disease experience an array of challenges and changes in daily living, behaviors, and functioning throughout the progression of their condition. The investigators want to learn more about the effects of Parkinson's Disease on individuals' social behavior and quality of life (QoL) compared to people of the same …

Accepts healthy volunteers
Online studies
  • 0 views
  • 02 Apr, 2026
  • Online study
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

macitentan 10 mg
macitentan
hypertension
left ventricular end-diastolic pressure
atrial septal defect
University of Florida
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +210 other locations
At-Risk for Type 1 Diabetes Extension Study

This study is an extension of the NIH-sponsored AT-Risk (TN-10) type 1 diabetes study (NCT 01030861). Teplizumab-treated and placebo-treated participants in the NIH trial who develop clinical type 1 diabetes after the conclusion of that trial, are eligible to enroll and receive teplizumab treatment within one year of diagnosis of …

teplizumab
type 1 diabetes mellitus
diabetes
Clinical Site
 (1.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients

A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration of induced hypothermia for neuroprotection in comatose survivors of cardiac arrest.

induced hypothermia
hypothermia
life support
coma
resuscitation
UF Health Shands Hospital
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
Durvalumab With or Without Olaparib as Maintenance Therapy After First-Line Treatment of Advanced and Recurrent Endometrial Cancer

A study to assess the efficacy and safety of durvalumab in combination with platinum-based chemotherapy (paclitaxel + carboplatin) followed by maintenance durvalumab with or without olaparib for patients with newly diagnosed advanced or recurrent endometrial cancer.

carcinoma
measurable disease
immunomodulator
carboplatin paclitaxel
platinum-based chemotherapy
Research Site
 (1.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +94 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

tumor markers
measurable disease
recurrent childhood medulloblastoma
recurrent thyroid gland carcinoma
nitrosoureas
University of Florida Health Science Center - Gainesville
 (1.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
Effect of Ketone Esters in Parkinson's Disease

Ketones esters have shown to improve mitochondrial function and are currently use to enhanced functional performance. As Mitochondrial dysfunction is one of the proposed mechanism of neuronal injury in Parkinson's disease, the study aims to assess the tolerability,side effects and effect of oral ketone esters in Patients with Parkinson's disease.

parkinson's disease
Fixel Institute for Neurological Diseases
 (3.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
AIM1: Adequate Selection of Patients for Thyroid Biopsy: Evaluation of a Shared Decision Making Conversation Aid

There is an epidemic of thyroid cancer that is harmful to patients and the medical system. The study hypothesizes that the use of an electronic conversation aid during clinical visits can help patients and clinicians collaborate when deciding the next step in management for a thyroid nodule. The study aims …

thyroid nodule
thyroid biopsy
aim1
cancer
University of Florida
 (1.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations