Altamonte Springs, Florida Clinical Trials

A listing of Altamonte Springs, Florida clinical trials actively recruiting patient volunteers.

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Found 40 clinical trials
Evaluation of the Integrated Radio Frequency Denervation System to Improve Glycemic Control in Type 2 Diabetic Subjects

The objective of this early feasibility study is to evaluate the safety and performance of intravascular hepatic denervation using the Metavention Integrated Radio Frequency Denervation System (iRF System) to improve glycemic control in type 2 diabetes subjects.

liver disease
fatty liver
hypertension
hypertension medication
nash
AdventHealth Translational Research Institute
 (6.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +4 other locations
Open-Label Study With Pimavanserin on Activities of Daily Living in Subjects With Parkinson's Disease Psychosis

To assess the effect of pimavanserin on the activities of daily living in subjects with Parkinson's Disease Psychosis

Neurology Associates, P.A.
 (2.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +18 other locations
Evaluation of the Efficacy and Safety of VX-864 in Subjects With the PiZZ Genotype

This study will evaluate the efficacy, safety and pharmacokinetics (PK) of VX-864 in PiZZ subjects.

Central Florida Pulmonary
 (7.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
tirzepatide
cardiovascular disease
dulaglutide
Orlando Heart & Vascular Institute, LLC
 (2.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168

Primary Objective: To assess efficacy of daily SAR442168 compared to a daily dose of 14 mg teriflunomide (Aubagio) measured by annualized adjudicated relapse rate (ARR) in participants with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance …

teriflunomide
urine test
multiple sclerosis
serum pregnancy test
pregnancy test urine
Investigational Site Number 8400004
 (2.7 away) Contact site
  • 0 views
  • 09 Sep, 2025
  • +24 other locations
Primary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor SAR442168 (PERSEUS)

Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary Objectives: To evaluate efficacy of SAR442168 compared to placebo on clinical endpoints, magnetic resonance imaging (MRI) lesions, cognitive performance, physical function, and quality of life To evaluate safety …

oligoclonal bands
Investigational Site Number 8400004
 (2.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +14 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

headache
ly573144
migraine
preventive medication
lasmiditan
Meridien Research
 (2.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +162 other locations
A Safety Study of Oral Venetoclax in Combination With Intravenous Pembrolizumab in Adult Participants With Previously Untreated Non-Small Cell Lung Cancer (NSCLC) With High Programmed Cell Death Ligand-1 (PD-L1) Expression

Non-Small Cell Lung Cancer (NSCLC) is a solid tumor, a disease in which cancer cells form in the tissues of the lung. It is the most common form of lung cancer, accounting for around 85% of lung cancers. The purpose of this study is to evaluate the safety and efficacy …

measurable disease
solid tumor
epidermal growth factor receptor
stage iv non-small cell lung cancer
drug test
AdventHealth Cancer Institute - Orlando /ID# 214444
 (6.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +38 other locations
Tipifarnib for the Treatment of Advanced Solid Tumors Lymphoma or Histiocytic Disorders With HRAS Gene Alterations a Pediatric MATCH Treatment Trial

This phase II pediatric MATCH trial studies how well tipifarnib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have HRAS genetic alterations. Tipifarnib may block the growth of cancer cells that have specific genetic changes in …

tumor markers
measurable disease
recurrent childhood medulloblastoma
recurrent thyroid gland carcinoma
nitrosoureas
AdventHealth Orlando
 (7.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +82 other locations
Pediatric KIDney Stone (PKIDS) Care Improvement Network

The goals of this study are to improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones and to enable urologists to use techniques that result in the best outcomes for these surgeries.

nephrolithiasis
nephrolithotomy
shock
ureterolithiasis
lithotripsy
AdventHealth Orlando
 (7.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +21 other locations