Sherman Oaks, California Clinical Trials

A listing of Sherman Oaks, California clinical trials actively recruiting patient volunteers.

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Found 70 clinical trials
A Study to Evaluate NT219 Alone and in Combination With ERBITUX (Cetuximab) in Adults With Advanced Solid Tumors and Head and Neck Cancer

This is a phase 1/2, multi-center study with an open-label, dose escalation phase followed by a single-arm expansion phase to assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and efficacy of NT219 alone and in combination with ERBITUX (cetuximab) in adults with recurrent and/or metastatic solid tumors.

erbitux
gilbert's syndrome
brain metastasis
carcinoma
measurable disease
The Angeles Clinic and Research Institute
 (7.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +5 other locations
Dupilumab Asthma Sleep Study

Primary Objective: To assess the effect of dupilumab on sleep Secondary Objectives: To evaluate the effect of dupilumab on additional patient reported sleep outcomes To evaluate the effect of dupilumab on objective sleep assessment To evaluate the effect of dupilumab on asthma symptoms To evaluate the effect of dupilumab on …

polysomnography
bronchodilator
dupilumab
pulmonary function test
leukotriene receptor antagonist
Investigational Site Number 8400009
 (6.8 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • +10 other locations
Study of ATI-2138 in Adult Participants with Moderate to Severe Atopic Dermatitis

This is a Phase 2 open label study of ATI-2138 in participants with moderate to severe atopic dermatitis.

Aclaris Investigational Site
 (2.4 away) Contact site
  • 0 views
  • 23 Jan, 2025
  • +4 other locations
Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Adults With Moderate to Severe Acne

The purpose of the trial is to evaluate the safety, efficacy and immunogenicity of up to 3 intramuscular injections of the Acne mRNA vaccine candidate at up to three dose levels in adult participants aged 18 to 45 years with moderate to severe acne. This trial will consist of a …

Unison Clinical Trials- Site Number : 8400025
 (0.6 away) Contact site
  • 0 views
  • 29 Nov, 2025
  • +30 other locations
THE ALIGN-AR PIVOTAL TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study

To collect information about treatment for symptomatic severe Aortic Regurgitation (AR), which affects the aortic valve in the heart. Aortic regurgitation is a condition where aortic valve in the heart does not close tightly and allows some blood to leak back into the heart chamber. Symptoms of aortic regurgitation may …

regurgitation
aortic valve replacement
shortness of breath
fatigue
Cedars Sinai Medical Center
 (6.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

prostatic neoplasm
measurable disease
prostatic neoplasms, castration-resistant
combined modality therapy
docetaxel
The University of California, Los Angeles
 (2.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +21 other locations
18F-DCFPyL PET/CT Impact on Treatment Strategies for Patients With Prostate Cancer

The main purpose of this phase II trial study is to determine whether a positron emission tomography (PET)/computed tomography (CT) scan using 18F-DCFPyL affects the clinical management plan in Veterans. In this study, the management plan prior to and after 18F-DCFPyL PET/CT will be recorded by specific questionnaires and corresponding …

prostate cancer metastatic
pet/ct scan
positron emission tomography
metastatic prostate cancer
definitive treatment
VA Greater Los Angeles Healthcare System
 (6.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

The ICGG Gaucher Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Gaucher disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The …

deficiency
imiglucerase
eliglustat
gaucher disease
Investigational Site Number 840108
 (9.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +220 other locations
Mucopolysaccharidosis I (MPS I) Registry

The Mucopolysaccharidosis I (MPS I) Registry is an ongoing, observational database that tracks the outcomes of patients with MPS I. The data collected by the MPS I Registry will provide information to better characterize the natural history and progression of MPS I as well as the clinical responses of patients …

Investigational Site Number 840108
 (9.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +135 other locations
Pompe Disease Registry

The Pompe Registry is an ongoing, international multi-center, strictly observational program that tracks the routine clinical outcomes for patients with Pompe disease, irrespective of treatment status. No experimental intervention is involved; patients in the Registry undergo clinical assessments and receive care as determined by the patient's treating physician. The objectives …

replacement therapy
glycogen storage disease type ii
gaa gene
deficiency
myozyme
Investigational Site Number 840108
 (9.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +190 other locations