Orange, California Clinical Trials

A listing of Orange, California clinical trials actively recruiting patient volunteers.

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Found 44 clinical trials
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

prostatic neoplasm
measurable disease
prostatic neoplasms, castration-resistant
combined modality therapy
docetaxel
The University of California, Irvine Medical Center
 (1.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +21 other locations
A Study of CRV431 Dosed Once Daily in NASH Induced F2 and F3 Subjects

This is a randomized, single-blind, placebo-controlled, once daily (QD) dose study of CRV431 in presumed NASH F2/F3 subjects.

fibroscan
fatty liver
vcte
hepatic fibrosis
fibrosis
Conquest Clinical Research
 (0.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
Development and Analysis of a Stool Bank for Cancer Patients

This study is aimed at understanding the impact of gut microbiota on efficacy of cancer therapies, in particular checkpoint inhibitors, and using the resulting information to design microbial immunotherapies. Although animal models are of use to determine the influences of gut and other microbiota on cancer treatment modalities, they are …

pembrolizumab
immunotherapies
cancer immunotherapy
cancer treatment
Compassionate Care Research Group, Inc.
 (7.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations
Patient-Derived Xenografts to Reduce Cancer Health Disparities

This trial establishes patient-derived cancer xenografts in addressing cancer health and treatment disparities that disproportionately affect racial/ethnic minorities. Understanding the genetic and response differences among racial/ethnic minorities may help researchers enhance the precision of therapeutic treatments.

lung cancer
liver cancer
cancer
biospecimen collection
bladder cancer
UC Irvine Health/Chao Family Comprehensive Cancer Center
 (1.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +1 other locations