Tempe, Arizona Clinical Trials

A listing of Tempe, Arizona clinical trials actively recruiting patient volunteers.

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Found 68 clinical trials
A Study of CAD106 and CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

The purpose of this study is to test whether two investigational drugs called CAD106 and CNP520, administered separately, can slow down the onset and progression of clinical symptoms associated with Alzheimer's disease (AD) in participants at the risk to develop clinical symptoms based on their age and genotype.

alzheimer's disease
mental state examination
mini-mental state examination
Accepts healthy volunteers
apolipoprotein e4
Banner Alzheimer's Institute
 (7.0 away) Contact site
  • 32 views
  • 20 Sep, 2024
  • +126 other locations
Enfortumab Vedotin and Pembrolizumab With or Without Chemotherapy vs. Chemotherapy Alone in Untreated Locally Advanced or Metastatic Urothelial Cancer

This study is being done to see how well two drugs (enfortumab vedotin and pembrolizumab) work together alone or with platinum chemotherapy to treat patients with urothelial cancer. The study will compare these drugs to other drugs that are usually used to treat this cancer (standard of care). The patients …

pd-l1
systemic therapy
immunomodulator
immunomodulators
carboplatin
Ironwood Cancer & Research Centers - Chandler
 (7.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +25 other locations
An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors

This study will evaluate the safety, tolerability, pharmacokinetics, and activity of XmAb24306 alone or in combination with a checkpoint inhibitor treatment in participants with locally advanced or metastatic solid tumors.

atezolizumab
solid neoplasm
serum pregnancy test
solid tumor
solid tumour
Honor Health Research Institute
 (10.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +12 other locations
Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension

The purpose of this study is to demonstrate superiority of macitentan 75 milligrams (mg) in prolonging the time to the first clinical events committee (CEC)-adjudicated morbidity or mortality (M/M) event in participants with symptomatic pulmonary arterial hypertension (PAH) compared to macitentan 10 mg.

patent ductus arteriosus
atrial septal defect
HIV Infection
septal defect
macitentan
Arizona Pulmonary Specialists, Ltd
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +210 other locations
A Study of Oral Upadacitinib Tablet Compared to Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa to Assess Change in Disease Symptoms

Hidradenitis suppurativa (HS) is an inflammatory skin disease that causes painful lesions in the axilla (underarm), inguinal (groin) and anogenital (anal and genital) regions. This study will evaluate how well upadacitinib compared to placebo (no medicine) works to treat hidradenitis suppurativa (HS) in adult participants with moderate to severe disease. …

Medical Dermatology Specialist /ID# 221084
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +27 other locations
Aging and Information Processing

The purpose of our study is to better understand functional differences in brain activity between healthy aging and neurodegenerative conditions, such as Alzheimer's Disease. To do this, our lab uses a noninvasive and inexpensive technique to collect brain measurements called electroencephalogram (EEG). By recording EEG while participants do certain memory …

Test Site 13
 (7.7 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +8 other locations
Efficacy and Safety Study of Frexalimab (SAR441344) in Adults With Nonrelapsing Secondary Progressive Multiple Sclerosis (FREVIVA)  

The purpose of this randomized, double-blind, placebo-controlled, parallel group study is to determine the efficacy of frexalimab in delaying the disability progression and the safety up to approximately 51 months administration of study intervention compared to placebo in male and female participants with nrSPMS (aged 18 to 60 years at …

Imaging EndPoints Site Number : 8400050
 (10.0 away)
  • 0 views
  • 04 Mar, 2025
  • +58 other locations
Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma (AIRLYMPUS)

This is a parallel-group, Phase 2, randomized, double-blind, placebo-controlled, 2-arm study for the treatment of asthma.The purpose of this study is to assess the efficacy, safety, and tolerability of add-on therapy with SC lunsekimig compared with placebo in male and female participants (aged 18 to 80 years, inclusive) with asthma, …

Chandler Clinical Research Trials- Site Number : 8400075
 (7.8 away) Contact site
  • 0 views
  • 24 Nov, 2025
  • +50 other locations
A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.

This is a multi-center, randomized, double-blind, placebo-controlled, parallel group 36 week multicenter Phase 2 study of two doses of CT1812 in adults with mild to moderate Alzheimer's Disease (AD).

Imaging Endpoints
 (10.0 away) Contact site
  • 0 views
  • 20 Sep, 2024
  • +10 other locations
Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) Before and During Treatment With Ocrelizumab

This is an open-label, multicenter study that includes a main study for all participants enrolled and an optional cerebrospinal fluid (CSF) sub-study. Self-identified African American (AA) and Hispanic or Latin American (HA) participants with a diagnosis of relapsing multiple sclerosis (RMS) will be enrolled. The treating neurologist must make an …

HonorHealth Neurology
 (5.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +30 other locations