Weston, Canada Clinical Trials

A listing of Weston, Canada clinical trials actively recruiting patients volunteers.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 64 clinical trials
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

cognitive deficit
sternotomy
coma
comatose
anesthetics
Sunnybrook Health Sciences Centre
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
mini-mental state examination
positron emission tomography
flortaucipir
alzheimer's disease
Toronto Memory Program
 (9.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
ZYNRELEF® for Postoperative Analgesia After Laparoscopic Sleeve Gastrectomy (HeronBariatric) PUBLISHED

Approximately 120 subjects will be randomized into 1 of the following 2 treatment groups in a 1:1 ratio:Group 1: ZYNRELEF® up to 200 mg/ 6mg ( 7ml vial) via instillation at all incision sites in addition to 30 ml of 0.5% Ropivacaine + 10mg dexamethasone. Postoperatively, intermittent IV acetaminophen will …

New Site for Canada
 (6.8 away) Contact site
  • 0 views
  • 12 May, 2025
  • +3 other locations
None

Sunnybrook Health Sciences Centre
 (7.0 away) Contact site
  • 0 views
  • 19 May, 2025
  • +19 other locations
A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

dementia
aphasia
pick's disease
progranulin
Sunnybrook Research Institute - University of Toronto
 (7.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +46 other locations
A Study of Lasmiditan (LY573144) Treatment in Children Aged 6 to 17 With Migraine

The reason for this study is to see if lasmiditan is safe and effective in children aged 6 to 17 with migraine. The study will last up to 20 weeks and may include up to 4 visits.

headache
ly573144
migraine
preventive medication
lasmiditan
Women's College Hospital
 (6.9 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +162 other locations
Treatment of Moderate to Severe Lateral Canthal Lines and Glabellar Lines Alone or in Combination

This study is designed to evaluate the safety and efficacy of a single dose of QM1114-DP for the treatment of moderate to severe LCL and moderate to severe GL, alone or in combination.

Bertucci Medspa, Inc
 (7.4 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:

Stereotactic Ablative Body Radiotherapy (SABR) given in 5 weekly fractions. Simultaneously treating the pelvic lymph nodes, prostate and MRI-nodule to a total dose of 25 Gy, 35 Gy and up to 50 Gy, respectively. The radiation will be given with 6-18 months of ADT. 5-fraction SABR is a feasible, well-tolerated, …

stereotactic body radiation therapy
adenocarcinoma of prostate
adenocarcinoma
Sunnybrook Health Sciences Center
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Hyperpolarized Imaging for New Treatments

The introduction of triple combination CFTR modulator therapy for patients with Cystic Fibrosis (CF) with at least one copy of the deltaF508 mutation is expected to provide major health benefits, but will also require novel outcome measures that can detect CF lung disease at an early stage, capture the efficacy …

antibiotic therapy
pulmonary disease
pulmonary function test
fibrosis
sweat test
The Hospital for Sick Kids
 (7.0 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +3 other locations
A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

kras g12c mutation
ki-ras
solid tumor
kras
metastatic malignant solid tumor
Princess Margaret Cancer Centre
 (6.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +7 other locations