Thornhill, Canada Clinical Trials

A listing of Thornhill, Canada clinical trials actively recruiting patients volunteers.

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Found 41 clinical trials
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Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 19 May, 2025
  • +19 other locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

dulaglutide
cardiovascular disease
tirzepatide
body mass index
LMC Endocrinology Centres Ltd.
 (1.6 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

cognitive deficit
cognitive deficits
dexmedetomidine
comatose
thoracotomy
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

alzheimer's disease
positron emission tomography
mini-mental state examination
flortaucipir
florbetapir
Toronto Memory Program
 (6.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
Treatment of Moderate to Severe Lateral Canthal Lines and Glabellar Lines Alone or in Combination

This study is designed to evaluate the safety and efficacy of a single dose of QM1114-DP for the treatment of moderate to severe LCL and moderate to severe GL, alone or in combination.

Bertucci Medspa, Inc
 (4.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +9 other locations
5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:

Stereotactic Ablative Body Radiotherapy (SABR) given in 5 weekly fractions. Simultaneously treating the pelvic lymph nodes, prostate and MRI-nodule to a total dose of 25 Gy, 35 Gy and up to 50 Gy, respectively. The radiation will be given with 6-18 months of ADT. 5-fraction SABR is a feasible, well-tolerated, …

stereotactic body radiation therapy
adenocarcinoma of prostate
adenocarcinoma
Sunnybrook Health Sciences Center
 (7.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Prone Positioning for Patients on General Medical Wards With COVID19

COVID-PRONE is a multicenter, pragmatic, single-blind, 2-arm, parallel, randomized controlled trial seeking to compare the pre-emptive prone positioning (i.e. encouraging patients to adopt a prone position before they require mechanical ventilation) to the control arm of standard care alone. Randomization will be stratified by site.

covid-19
nosocomial infection
FIO2
mechanical ventilation
fraction of inspired oxygen (fio2)
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
An Investigation on the Effects of Icosapent Ethyl (VascepaTM) on Inflammatory Biomarkers in Individuals With COVID-19

This is a 14-day long prospective, multi-site, two-armed, randomized, open-label study that will enroll approximately 100 adult outpatients in Canada who have received a positive SARS-CoV-2 test result within the preceding 72 hours. Participants will be randomized (1:1) to receive either icosapent ethyl (4 g BID for 3 days, then …

SARS
dyspnea
pharyngitis
sore throat
fever
North York Diagnostic and Cardiology Clinic
 (7.1 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer

In this study, PA imaging will be used to examine the physiological and physical changes in lymph node involvements of head and neck cancer during radiotherapy with or without chemotherapy. Our objective in this pilot study will be to evaluate if PA parameters change within the lymph node involvements during …

renal function test
head and neck cancer
neck cancer
chemoradiotherapy
carcinoma
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy

Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumors during chemotherapy treatment over time.

breast mass
locally advanced breast cancer
advanced breast cancer
HER2
breast neoplasm
Sunnybrook Health Sciences Centre
 (7.2 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location