a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1959 clinical trials
Oral EPI-7386 in Patients With Metastatic Castration-Resistant Prostate Cancer

This is a phase I, clinical research study of EPI-7386, an investigational drug being studied as a treatment for patients with prostate cancer.

bone lesion
diphosphonates
metastasis
castration-resistant prostate cancer
progressive disease
  • 0 views
  • 19 Feb, 2024
  • 5 locations
The Effect of Time-Restricted Eating in Cardiometabolic Health

However, an understanding of the effect of TRE on cardiometabolic health in people is not clear and few studies have evaluated this issue. Accordingly, the investigators propose to conduct a randomized controlled trial in people with obesity and prediabetes to determine the effect of 9 h TRE for 12 weeks, …

cardiovascular disease
glucose intolerance
insulin sensitivity
glycosylated hemoglobin
plasma glucose
  • 0 views
  • 19 Feb, 2024
  • 1 location
The Effect of Hepatic Impairment on Aprocitentan Pharmacokinetics

This is a prospective, single-center, open-label, single-dose, Phase 1 study, to assess the effect of moderate hepatic impairment due to liver cirrhosis on the pharmacokinetics of aprocitentan (ACT-132577).

moderate hepatic impairment
renal function test
oophorectomy
kidney function tests
renal function
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study of Tumor Infiltrating Lymphocytes Following CCRT in the Treatment of Patients With Cervical Carcinoma

A Phase II trial to study the effectiveness and security of cisplatin concurrent chemoradiotherapy plus TIL versus cisplatin concurrent chemoradiotherapy only in treating patients with FIGO stage IIIA to IVA cervical carcinoma.

cervical carcinoma
cisplatin
cervical cancer
squamous cell carcinoma
adenocarcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Evaluating the Clinical Value of Traditional Chinese Medicine in the Adjuvant Therapy of Triple-negative Breast Cancer

This is a prospective, single site, randomized, double-blind Phase III clinical trial to evaluate the clinical value of Traditional Chinese Medicine in the adjuvant therapy of triple-negative breast cancer patients.

metastasis
progesterone
platelet count
traditional chinese medicine
triple-negative breast cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

This is a Phase 1b/2, open-label, multicenter platform trial to evaluate the antitumor activity and safety of AB928-based combination therapy in participants with metastatic castrate resistant prostate cancer (mCRPC).

antiandrogen therapy
prostatic neoplasm
antiandrogens
docetaxel
castration-resistant prostate cancer
  • 0 views
  • 19 Feb, 2024
  • 22 locations
Wearable Monitoring Systems for Swallowing Function and Disorders

Wearable tele-rehabilitation technology allows for the efficient provision of rehabilitation services from a distance, facilitating tele-management of many disorders. The proposed research will develop and validate a set of mechanically compliant, easy-to-use, and inexpensive wearable tele-monitoring systems, for future use in the rehabilitation of swallowing disorders (dysphagia).

stroke
parkinson's disease
neurological disorder
dysphagia
  • 0 views
  • 19 Feb, 2024
  • 1 location
Hyperpolarized Imaging for New Treatments

Magnetic resonance imaging (MRI) has the advantage of being a radiation-free modality, making it more suitable for assessing response to therapy in a shorter time frame with repeated imaging.

multiple breath washout
pilocarpine
sweat test
pulmonary function test
antibiotics
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Multi Neuro-functional Biomarkers for Monitoring the Effects of Treatments in ADHD Children

ADHD group is evaluated before the beginning of medications, at first dose of medication (only imaging evaluation fNIRS), and after a period of two/three months of continuous treatment with medication.

attention deficit hyperactivity disorder
hyperactivity
deficit
attention deficit disorder
psychiatric disorders
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pilot Study to Evaluate the Effect of Nicotinamide Riboside on Immune Activation in Psoriasis

These will be from both lesions and unaffected areas. The areas will be injected with a numbing medicine. A round cutting device will remove small pieces of skin from each area. Participants will take the study supplement or a placebo starting at the first visit.

vitamins
chronic inflammation
psoriasis
urine test
niacin
  • 0 views
  • 19 Feb, 2024
  • 1 location