a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1959 clinical trials
Acute and Long-Term Antidepressant Treatment Success in Adolescents With Anxiety (AtLAS-A)

Acute, double-blind, adaptively randomized treatment with duloxetine or escitalopram, followed by open-label naturalistic follow-up.

evra
urine drug screen
separation
depo-provera
nuvaring
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Phase I/Ib Study of NIZ985 Alone and in Combination With Spartalizumab

Moreover, the study will characterize the pharmacokinetic profiles of NIZ985 as a single agent and in combination with Spartalizumab and identify preliminary anti-tumor activity.

  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease

The purpose of this study is to evaluate the safety of Guselkumab in participants with Crohn's disease.

ileocolitis
ileitis
endoscopy
crohn's disease
colitis
  • 0 views
  • 19 Feb, 2024
  • 11 locations
A Long Term Follow-Up Study of Fabry Disease Subjects Treated With FLT190

Fabry disease is a rare, X-linked inborn error of glycosphingolipid metabolism caused by an abnormal gene encoding the -galactosidase A (GLA) enzyme.

deficiency
gene therapy
glycosphingolipids
fabry's disease
breakdown
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation

We are going to evaluate the difference between perioperative intravenous steroid supplementation, perioperative periarticular steroid supplementation, and standard anaesthesia protocols. We'll evaluate the outcome of patients with knee osteoarthritis who are undergoing Total Knee Arthroplasty to understand which of the three treatments give more benefits to the patient.

total knee replacement
dexamethasone
anesthesia
dexamethasone sodium phosphate
osteoarthritis
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Evaluate the Safety Tolerability Pharmacokinetics and Preliminary Efficacy of CN1

This study is the first-in-human clinical trial of CN1 to evaluate the safety, tolerability, pharmacokinetic (PK) profile and preliminary efficacy of CN1 in patients with advanced solid tumors or B-cell lymphoma. This study will provide a basis for further clinical development of CN1.

lymphoma
solid tumour
b-cell lymphoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of BLYG8824A in Participants With Locally Advanced or Metastatic Colorectal Cancer

This study will evaluate the safety, tolerability, and pharmacokinetics of BLYG8824A and will make a preliminary assessment of the anti-tumor activity of BLYG8824A in patients with locally advanced or metastatic colorectal cancer.

irinotecan
colorectal cancer
metastatic colorectal cancer
oxaliplatin
combination therapy
  • 0 views
  • 19 Feb, 2024
  • 6 locations
A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)

It is known that people with ILD are highly inactive and sedentary, and in a severe stage of the disease, these people spend most of the time at home, increasing dependency on others, and decrease HRQoL. Physical activity is a cost-effective intervention, which increases the HRQoL, exercise capacity and ability …

  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS CMML or AML

Study ASTX030-01 is designed to move efficiently from Phase 1 to Phase 3. Phase 1 consists of an open-label Dose Escalation Stage (Stage A) using multiple cohorts at escalating dose levels of oral cedazuridine and azacitidine (only one study drug will be escalated at a time) followed by a Dose …

myelodysplastic/myeloproliferative neoplasm
chronic myelomonocytic leukemia
cedazuridine
ringed sideroblasts
graft versus host disease
  • 0 views
  • 19 Feb, 2024
  • 2 locations
A Multicentre Non-Blinded Study Exploring Self-Administration of Chemotherapy in the Home Environment

This study is to see if the standard of care subcutaneous injection of bortezomib can safely be administered at home by the patient or caregiver. All tests and assessments are based on standard of care procedures.

cancer
multiple myeloma
bortezomib
  • 0 views
  • 24 Nov, 2025
  • 1 location