a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

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Found 1959 clinical trials
PB2452 in Ticagrelor-treated Patients With Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure

This is a multi-center, open-label, prospective single-arm study of reversal of the antiplatelet effects of ticagrelor with PB2452 in patients who present with uncontrolled major or life-threatening bleeding or who require urgent surgery or invasive procedure.

packed red blood cells
blood transfusion
ticagrelor
heart surgery
haemostasis
  • 0 views
  • 19 Feb, 2024
  • 6 locations
An N-of-1 Trial of an Internet-delivered CBT Program Based on the Psychological Flexibility Model of Chronic Pain for Cancer-related Difficulties

<p>Chronic pain is a commonly occurring complication of cancer but access to the first-line recommended treatment (pain-focused cognitive behavioral therapy - CBT) is limited outside of specialist pain clinics in Sweden, and these clinics do not routinely accept people with cancer-related pain.

  • 0 views
  • 15 Jan, 2025
  • 1 location
CPAP on Acute Stroke and OSA

Recently, several studies showed that enlarged left atrium (LA) can serve as a predictor for recurrent stroke or cardiovascular events. On the other hand, a growing body of studies demonstrated that CPAP treatment reduce size of LA in those with OSA.

recurrent strokes
central sleep apnea
continuous positive airway pressure
acute coronary syndrome
stroke
  • 0 views
  • 19 Feb, 2024
  • 1 location
OCT Evaluation of Early Vascular Repair in Patients With Non ST Elevation Acute Coronary Syndrome (NSTE-ACS)

This is a prospective study of a new generation of drug-eluting stent in the treatment of non ST elevation acute coronary syndrome (NSTE-ACS).

coronary disease
infarct
aspirin
antiplatelet therapy
bypass graft
  • 0 views
  • 19 Feb, 2024
  • 2 locations
The Effect of Inflammation and Damage to Lymph Node Structures on Durable Protective Immunity Following Vaccination

This protocol will study yellow fever vaccine (YFV) in two cohorts of people, one from Uganda and the other from Minnesota where we collect lymphoid tissues (LT) and peripheral blood monocytes (PBMCs) before and after vaccination using a new technique to catalog infectious burden of the individual, determine the relationship …

immunosuppressive
vaccination
yellow fever
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Comparative Efficacy of Pregabalin and Lacosamide in Patients With Herpes Zoster and Post Herpetic Neuralgia  

PHN is characterized by neuropathic pain lasting beyond the resolution of the rashes. Post herpetic neuralgia (PHN) represents a potentially debilitating and often undertreated form of neuropathic pain that disproportionately affects vulnerable populations, including the elderly and the immunocompromised.

  • 0 views
  • 03 Dec, 2025
  • 1 location
Effects of Transcranial Direct Current Stimulation Associated With Cognitive Training in Alzheimer's Disease

Alzheimer's disease (AD) is characterized by a progressive decline in cognitive functions, interfering with autonomy and independence. According to the Diagnostic and Statistical Manual of Mental Disorders (DSM 5), mnemonic dysfunction in AD must be related to aphasia, apraxia, agnosia, or changes in executive function.

behavioral symptoms
aphasia
mini-mental state examination
psychiatric disorder
alzheimer's disease
  • 0 views
  • 19 Feb, 2024
  • 1 location
Clinical Utility of Liquid Biopsy in Brigatinib ALK+ Patients

Patient accrual is expected to be completed within 1.5 years excluding a run-in-period of 4-6 months. Treatment and follow-up are expected to extend the study duration to a total of 5 years. Patients will be followed for 1 year after the end of treatment independently of the cause of end …

transient ischemic attack
aptt
lipase
hepatitis b surface antigen
lung cancer
  • 0 views
  • 19 Feb, 2024
  • 15 locations
Intervening With Opioid-Dependent MothersMothers and Infants

The investigators expect that mothers who receive the modified Attachment and Biobehavioral Catch-up Intervention will show more nurturing and sensitive parenting and more adaptive physiological regulation than parents who receive a control intervention. The investigators expect that infants whose mothers receive the modified Attachment and Biobehavioral Catch-up will show better …

opioid
narcotic use
opioid use disorder
  • 0 views
  • 19 Feb, 2024
  • 1 location
An Advance Care Planning Programme for Persons With Early Stage Dementia or Mild Cognitive Impairment in the Community

This proposed study attempts to promote the uptake of ACP for this population and their family caregivers in the community and to examine the effects of an ACP programme "Have a Say" for this population. It is hypothesized that participants in the intervention group will be more engaged in ACP …

dementia
mild cognitive impairment
cognitive impairment
  • 0 views
  • 19 Feb, 2024
  • 4 locations