Markham, Canada Clinical Trials

A listing of Markham, Canada clinical trials actively recruiting patients volunteers.

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Found 39 clinical trials
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
tirzepatide
cardiovascular disease
dulaglutide
LMC Endocrinology Centres Ltd.
 (8.3 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +650 other locations
Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

Anesthesia is a drug induced, reversible, comatose state that facilitates surgery and it is widely assumed that cognition returns to baseline after anesthetics have been eliminated. However, many patients have persistent memory impairment for weeks to months after surgery. Cardiac surgery appears to carry the highest risk of postoperative cognitive …

cognitive deficit
sternotomy
coma
comatose
anesthetics
Sunnybrook Health Sciences Centre
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

The reason for this study is to see how safe and effective the study drug donanemab is in participants with early Alzheimer's disease.

florbetapir
mini-mental state examination
positron emission tomography
flortaucipir
alzheimer's disease
Toronto Memory Program
 (6.8 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +85 other locations
None

Sunnybrook Health Sciences Centre
 (9.5 away) Contact site
  • 0 views
  • 19 May, 2025
  • +19 other locations
5 Fractions of Pelvic SABR With Intra Prostatic SABR Boost:

Stereotactic Ablative Body Radiotherapy (SABR) given in 5 weekly fractions. Simultaneously treating the pelvic lymph nodes, prostate and MRI-nodule to a total dose of 25 Gy, 35 Gy and up to 50 Gy, respectively. The radiation will be given with 6-18 months of ADT. 5-fraction SABR is a feasible, well-tolerated, …

stereotactic body radiation therapy
adenocarcinoma of prostate
adenocarcinoma
Sunnybrook Health Sciences Center
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Prone Positioning for Patients on General Medical Wards With COVID19

COVID-PRONE is a multicenter, pragmatic, single-blind, 2-arm, parallel, randomized controlled trial seeking to compare the pre-emptive prone positioning (i.e. encouraging patients to adopt a prone position before they require mechanical ventilation) to the control arm of standard care alone. Randomization will be stratified by site.

FIO2
mechanical ventilation
covid-19
nosocomial infection
fraction of inspired oxygen (fio2)
Sunnybrook Health Sciences Centre
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • +6 other locations
Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer

In this study, PA imaging will be used to examine the physiological and physical changes in lymph node involvements of head and neck cancer during radiotherapy with or without chemotherapy. Our objective in this pilot study will be to evaluate if PA parameters change within the lymph node involvements during …

carcinoma
chemoradiation therapy
measurable disease
neutrophil count
renal function test
Sunnybrook Health Sciences Centre
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy Pilot Study to Evaluate Photoacoustic Imaging for Characterizing Breast Masses and Breast Tumor Response to Neoadjuvant Chemotherapy

Our objective in this pilot study will be to identify PA parameters that can distinguish benign vs. malignant lesions, and also, if PA parameters change with within breast tumors during chemotherapy treatment over time.

HER2
advanced breast cancer
breast mass
breast neoplasm
locally advanced breast cancer
Sunnybrook Health Sciences Centre
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location
The Sunnybrook Type 2 Diabetes Study

The Sunnybrook Type 2 Diabetes Study (S2DS) is a prospective observational study of people with prediabetes or Type 2 Diabetes Mellitus (T2DM), that aims to understand the aetiologies, manifestations, and clinical consequences of mood and cognitive complications. The study recruits from the services at Sunnybrook Health Sciences Centre and from …

type 2 diabetes mellitus
glycosylated hemoglobin
cardiac rehabilitation
hemoglobin a1c
impaired glucose tolerance
Sunnybrook Research Institute
 (9.5 away) Contact site
  • 0 views
  • 19 Feb, 2024
  • 1 location