Downsview Ontario, Canada Clinical Trials
A listing of Downsview Ontario, Canada clinical trials actively recruiting patients volunteers.
Found 66 clinical trials
מחקר להערכת הבטיחות, היעילות והאימונוגניות של חיסון mRNA לאקנה במבוגרים עם אקנה בינונית עד חמורה
מטרת הניסוי היא להעריך את הבטיחות, היעילות והאימונוגניות של עד 3 זריקות תוך שריריות של חיסון mRNA לאקנה בעד שלוש רמות מינון במשתתפים בוגרים בגילאי 18 עד 45 עם אקנה בינונית עד חמורה.
- 0 views
- 10 Sep, 2025
- +21 other locations
A Medical Research Study Designed to Determine if Venglustat Can be a Future Treatment for ADPKD Patients
Primary Objective: To determine the effect of venglustat on the rate of total kidney volume (TKV) growth (Stage and estimated glomerular filtration rate (eGFR) decline in patients at risk of rapidly progressive Autosomal Dominant Polycystic Kidney Disease (ADPKD) (Stage 2). Secondary Objectives: To determine the effect of venglustat on the …
- 0 views
- 19 Feb, 2024
- +80 other locations
Safety and Efficacy of Eliglustat With or Without Imiglucerase in Pediatric Patients With Gaucher Disease (GD) Type 1 and Type 3
Primary Objective: Evaluate the safety and pharmacokinetics of eliglustat in pediatric patients (2 to <18 years old). Secondary Objective: Evaluate the efficacy of eliglustat and quality of life in pediatric patients (2 to <18 years old).
- 0 views
- 19 Feb, 2024
- +22 other locations
Benefits of Exercise in Alzheimer's Disease
Exercise has been shown to be beneficial for the brain. The investigators would like to test this specifically for those diagnosed with Alzheimer's disease. This study will involve 30 randomized patients to take part in the out-patient exercise program and 30 patients to continue with their regular activities over a …
- 4 views
- 19 Feb, 2024
- 1 location
Precision Orthodontics: A Comparison of Custom vs Traditional Bracket Treatment Efficiency
This investigational testing aims to target multiple investigations sites to examine treatment efficiency metrics using a completely digital and patient-specific bracket treatment system for the correction of malocclusions.
- 0 views
- 19 Feb, 2024
- +2 other locations
Blood-Brain-Barrier Disruption With Cerezyme in Patient's With Parkinson's Disease
This clinical trial focus on the delivery of Cerezyme in Parkinson's Disease (PD) patients using MR-guided focused ultrasound (MRgFUS) induced opening of the blood-brain barrier (BBB).
- 16 views
- 19 Feb, 2024
- 1 location
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Locally-Advanced Breast Cancer
The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.
- 0 views
- 19 Feb, 2024
- 1 location
First in Human Study of M6223 in Participants With Metastatic or Locally Advanced Solid Unresectable Tumors
The main purpose of this study is to determine the safety, tolerability, pharmacokinetics (PK), immunogenicity and (if observed) the maximum tolerated dose (MTD) of M6223 as a single agent (Part 1A) and of M6223 combined with bintrafusp alfa (Part 1B) in participants with metastatic or locally advanced solid unresectable tumors.
- 0 views
- 19 Feb, 2024
- +3 other locations
Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Head and Neck Cancer
The objective of this study is to demonstrate the feasibility of novel MRI-guided ultrasound stimulated microbubble treatment to enhance radiation effects in humans receiving external beam radiotherapy delivered using a LINAC (linear accelerator) radiation therapy device.
- 0 views
- 19 Feb, 2024
- 1 location
Topotecan Episcleral Plaque for Treatment of Retinoblastoma
This single site, single-arm, non-randomized, dose escalation phase I toxicity clinical trial will assess primarily the safety and secondarily the efficacy of episcleral topotecan in patients with active residual or recurrent intraocular retinoblastoma in at least one eye following completion of first-line therapy.
- 0 views
- 19 Feb, 2024
- 1 location