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Neoplasm Metastasis Clinical Trials

A listing of Neoplasm Metastasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 526 clinical trials

E Erin Watters

The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

Use of indocyanine green will augment the accuracy of identification and resection of both primary solid malignancies as well as their pulmonary metastases, where applicable We will conduct a prospective feasibility study of pediatric patients with solid malignancies with or without lung metastatases who present at the time of initial …

45 years and younger All Phase N/A
R Robert Lewandowski, MD

Optimizing Y90 Therapy for Radiation Lobectomy

HCC resection candidates with inadequate future liver remnant will be enrolled in this study. They will be treated with Y90 radioembolization to help grow the liver enough to undergo liver resection. There will be 2 Patient Groups. The first group of patients will be treated with Y90 dose and embolic …

18 years and older All Phase N/A
F Fabio Martinelli, MD

The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.

The role of small-volume lymph node disease (ITC and micro metastases) among patients with endometrial or cervical cancer submitted to sentinel node (SLN) procedure is not clearly defined. This study was designed to create a dataset of patients with lymph nodal disease. Data on type and volume of lymph nodal …

18 years and older Female Phase N/A
Z Zoya Bauer

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

This phase II study investigates how well radium-223 works in treating patients with castration-resistant prostate cancer than has spread to the bones (bone metastases). Prostate cancer is the most common cancer in men and the second leading cause of cancer death. Furthermore, many men with notably advanced disease have been …

18 years and older Male Phase N/A
C Charles TACQUARD, MD

Thromboembolic Events in Severe COVID-19 Patients

The main objective of this study is to describe the incidence of thromboembolic events in a population of patients hospitalized in intensive care units in France for severe COVID-19. The secondary objective of this study is to describe the evolution of hemostasis parameters during the first two weeks of intensive …

18 years and older All Phase N/A
H Hany Eldhahaby, MD

Surface Landmarks and C-length as Predictors of Depth of Right IJV Catheter Insertion: A TEE-Guided Study

The primary aim of the current study is to examine the accuracy of the C-distance or surface landmarks in determining the length of central venous catheter (CVC) that is required to place the catheter tip at the mid-superior vena cava (SCV) as confirmed by transesophageal echocardiography (TEE). A secondary aim …

18 years and older All Phase N/A
M Merve Orucu Atar

The Assessment of Talar Cartilage in Patients With Unilateral Traumatic Transtibial Amputation

Increased risk of osteoarthritis (OA) has been previously demonstrated in patients with lower limb amputation. Although there are many studies on knee joint of intact limb of amputees in the literature, the number of studies on intact foot and ankle is extremely limited. The primary aim of the study is …

18-65 years All Phase N/A
S Susana Puig Sardà, PhD, MD

Understanding the Transition from Normal Melanocytes to Nevus to Melanoma

The primary objective of this study is to identify the molecular identity profiles of all cellular states that characterize the progression from benign nevi to malignant melanoma in CAYA patients with L/GCMN. The secondary objectives are:To longitudinally characterize the cell-free DNA (cfDNA) from CAYA patients.To improve the early diagnosis and …

60 years and younger All Phase N/A

Study of the Thyroid Function and Echostructural Morphology in Patients Affected With Rasopathies (ECORAS2023)

The study aims to evaluate the prevalence of thyroid disease, particularly with autoimmune pathogenesis (isolated hyperthyrotropinemia, hyperthyroidism, hypothyroidism, thyroid nodules) and/or morphostructural abnormalities of the thyroid gland in patients with RASopathy genetically confirmed by NGS technique (analysis of the genes: BRAF, CBL, HRAS, KRAS, LZTR1, MAP2K1, MAP2K2, MRAS, NRAS, PPP1CB, …

3-25 years All Phase N/A
A Aleksandra Gąsecka, PhD

TMAO in Patients With Severe Aortic Stenosis

Trimethylamine N-oxide (TMAO) has recently gained increasing scientific interest in the field of cardiovascular disease, including its role in cell protection against osmotic and hydrostatic stress. Aortic stenosis (AS) is the most common valvular heart disease, affecting about 7.6 million people over 75 years of age in North America and …

18-99 years All Phase N/A

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