Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 3503 clinical trials
A Trial of Adding Lung Protective Strategies to Existing Enhanced Recovery After Surgery (ERAS) Protocols and Its Effects on Improving Post-Operative Lung Function

The objective of this study is to determine whether the addition of lung protective strategies to existing enhanced recovery after surgery (ERAS) protocols for colorectal surgeries and hepatobiliary surgeries will improve post-operative lung function.

enhanced recovery after surgery
musc
  • 0 views
  • 19 Feb, 2024
  • 1 location
PB2452 in Ticagrelor-treated Patients With Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure

This is a multi-center, open-label, prospective single-arm study of reversal of the antiplatelet effects of ticagrelor with PB2452 in patients who present with uncontrolled major or life-threatening bleeding or who require urgent surgery or invasive procedure. Approximately 200 patients will be enrolled at approximately 200 centers worldwide. Patients with reported …

blood transfusion
orthopedic surgery
systolic blood pressure
heart surgery
postoperative hemorrhage
  • 0 views
  • 19 Feb, 2024
  • 6 locations
Training Single Arm

The pulmonary hypertension is a disease, which tends to a progredient right heart failure. Although there was a large progress in development of medical therapy, the quality of life, the physical efficiency and the prognosis of the patients are still limited. The aim of the study is to examine the …

medical therapy
hypertension
heart failure
right heart catheterization
right ventricular failure
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation

We are going to evaluate the difference between perioperative intravenous steroid supplementation, perioperative periarticular steroid supplementation, and standard anaesthesia protocols. We'll evaluate the outcome of patients with knee osteoarthritis who are undergoing Total Knee Arthroplasty to understand which of the three treatments give more benefits to the patient.

dexamethasone sodium phosphate
total knee replacement
osteoarthritis
anesthesia
dexamethasone
  • 0 views
  • 19 Feb, 2024
  • 1 location
Plasma Radiofrequency Ablation at Low Temperature Versus Electrocautery Block Resection at High Frequency for Localized Recurrent Nasopharyngeal Carcinoma

This study aims at exploring whether plasma radiofrequency ablation at low temperature is associated with better survival outcome in localized recurrent nasopharyngeal carcinoma by conducting a randomized controlled trial of plasma radiofrequency ablation at low temperature versus electrocautery block resection at high frequency for localized recurrent nasopharyngeal carcinoma. If the …

radiofrequency ablation
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Impact of a Double-reading Animated Film (Child Parents) in Preoperative on the Anxiety of Children Upon Arrival at the Operating Room

Preoperative anxiety affects 40 to 60% of children. A literature review concluded that effective preparation strategies must involve parents, must be appropriate to their age and proposed upstream of the intervention. A double-readinganimated film aimed at informative was created for the children and their parents/legal guardians in order to solve …

anxiety
  • 0 views
  • 19 Feb, 2024
  • 1 location
Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer

Additionally, the 8-12 week rest period from the end of the chemoradiotherapy and the radical surgery, treatment with durvalumab may continue improving the response and outcome of patients without jeopardizing the surgery (which needs this period out of chemotherapy and radiotherapy to avoid postoperative complications, but not for anti-PDL-1 therapy).

diverticulosis
oxaliplatin
carcinoma
organ transplantation
lccrt
  • 0 views
  • 19 Feb, 2024
  • 10 locations
Optimal Timing of BR55 CEUS of the Ovaries

This is an exploratory, single center, open label, prospective study of BR55 to determine the optimal phase of the menstrual cycle for performing BR55 CEUS of the target ovary in premenopausal women scheduled to undergo preventative surgery because of high familial/hereditary or genetic risk for ovarian cancer.

congestive heart failure
tubal ligation
systemic therapy
hypertension
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Longitudinal Immune-phenotyping of HCC Following MK-3475

In the main study, patients will be treated with pembrolizumab as neoadjuvant treatment approximately 4 weeks prior scheduled surgery. Adjuvant treatment with pembrolizumab with commence at approximately 4 weeks post-surgery for up to 12 months. Subjects will be followed up for a further 12 months after end of treatment for …

blood transfusion
prothrombin
hepatitis b surface antigen
aptt
adjuvant
  • 0 views
  • 19 Feb, 2024
  • 1 location
Neo-TACE-HAIC for BCLC B Stage HCC (Neoconcept)

Whether TACE-HAIC would improve survival for patients with BCLC B stage is need to further to study. A randomized clinical trial compared neo-TACE-HAIC with surgery versus surgery alone is aimed to answer this question.

oxaliplatin
carcinoma
TACE
chemoembolization
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location