Rectal Disorders Clinical Trials

A listing of Rectal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 27 clinical trials
A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

ki-ras
solid tumor
kras
kras g12c mutation
solid tumour
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  • 19 Feb, 2024
First-in-Human Dose Escalation Trial of ATRC-101 in Adults With Advanced Solid Malignancies

ATRC-101-A01 is a first-in-human, Phase 1b, open-label trial to characterize the safety, tolerability, pharmacokinetics (PK), and biological activity of escalating doses of ATRC-101, an engineered, fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a naturally-occurring human antibody.

blood transfusion
ovarian ca
cancer therapy
cancer of the ovary
ovarian cancer
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  • 19 Feb, 2024
Multicenter Study of Hypofractionated Postoperative Radiotherapy in Patients Diagnosed With Prostate Carcinoma

The objective of this study is to evaluate, in patients diagnosed with prostate cancer who undergo radical prostatectomy and who require postoperative radiotherapy, tolerance in terms of acute and chronic GU and GI toxicity and efficacy in terms of biochemical control and survival, as well as of quality of life, …

digital rectal examination
carcinoma
immunological adjuvant
bone scan
prostatectomy
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  • 19 Feb, 2024
Impact of Obsidian ASG on Anastomotic Healing

The use of regenerative medicine in colorectal surgery constitutes an entirely new therapeutic principle. The aim of this new therapeutic approach is to reduce the anastomotic leak rate and minimise morbidity and mortality. The literature identifies the leak rate for colorectal operations as 3-39%.

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  • 19 Feb, 2024
Collection of Information to Better Understand Young Onset Colorectal Cancer

The purpose of this registry study is to create a databasea collection of informationfor better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this …

inflammatory bowel disease
enteropathy
colorectal cancer
adenocarcinoma
colorectal adenocarcinoma
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  • 19 Feb, 2024
Locally Advanced Colorectal Cancer and Local Recurrences in V stra G taland

The aim of this study is to review the treatment strategies of locally advanced colorectal cancer and locally recurrent rectal cancer in Vstra Gtaland during 1995-2016. The aim is to evaluate time trends and outcome both related to morbidity and cancer specific survival, we will also evaluate the results after …

colorectal cancer
rectal cancer
cancer surgery
rectal carcinoma
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  • 19 Feb, 2024
Improving Colonoscopy Quality for Colorectal Cancer Screening in the National VA Healthcare System

High quality screening colonoscopy is critical for colorectal cancer (CRC) prevention in Veterans. There is significant variability in colonoscopy quality in VA that is directly linked to differences in CRC incidence and death. The investigators developed the VA Endoscopy Quality Improvement Program (VA-EQuIP) that the National GI program office will …

endoscopy
screening colonoscopy
colorectal cancer screening
adenoma
screening for colorectal cancer
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  • 19 Feb, 2024
BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer

The BESPOKE CRC study will prospectively enroll patients who have undergone surgery for stage II or III colorectal cancer (CRC) and who have residual formalin-fixed paraffin-embedded (FFPE) tissue available will provide FFPE and whole blood samples. Patients will receive SIGNATERA test results and may be recommended for adjuvant chemotherapy or …

adjuvant chemotherapy
adenocarcinoma of the colon
adjuvant
cancer
adenocarcinoma of colon
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  • 19 Feb, 2024
Advanced Geriatric Evaluation and Quality of Life in Colorectal Cancer Surgery

Colorectal cancer (CRC) disproportionately affects patients aged 70 years and older. Surgery is the main treatment modality for CRC, but is associated with increased risk of postoperative morbidity, disability and loss of health related quality of life (HRQL).Frailty is an age related state of functional decline and considered to be …

colorectal cancer
metastatic colorectal cancer
cancer surgery
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  • 19 Feb, 2024
Colorectal Cancer Awareness Research and Education and Screening - Rural Expansion Access and Capacity for Health

This study is to assess the impact of the CARES-REACH intervention on colorectal cancer screening rates.

colorectal cancer
cancer screening
colorectal cancer screening
screening for colorectal cancer
  • 0 views
  • 19 Feb, 2024