Rectal Disorders Clinical Trials
A listing of Rectal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 195 clinical trials
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
AGX101 is an antibody-drug conjugate (ADC) therapy for tumor-forming cancers. The purpose of this study is to learn about AGX101 effects and safety at various dose levels in an all-comers advanced solid cancer patient population. AGX101will be administered intravenously.Dosing of AGX101 will be repeated once every 3, 6 or 9 …
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- 24 Apr, 2026
Multicenter Study of Hypofractionated Postoperative Radiotherapy in Patients Diagnosed With Prostate Carcinoma
The objective of this study is to evaluate, in patients diagnosed with prostate cancer who undergo radical prostatectomy and who require postoperative radiotherapy, tolerance in terms of acute and chronic GU and GI toxicity and efficacy in terms of biochemical control and survival, as well as of quality of life, …
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- 19 Feb, 2024
- 19 locations
Impact of Obsidian ASG on Anastomotic Healing
The use of regenerative medicine in colorectal surgery constitutes an entirely new therapeutic principle. The aim of this new therapeutic approach is to reduce the anastomotic leak rate and minimise morbidity and mortality. The literature identifies the leak rate for colorectal operations as 3-39%.
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- 19 Feb, 2024
- 1 location
Collection of Information to Better Understand Young Onset Colorectal Cancer
The purpose of this registry study is to create a databasea collection of informationfor better understanding young onset colorectal cancer. Colorectal cancer patients are considered to have young onset colorectal cancer if they are diagnosed with their cancer before the age of 50. Researchers will use the information from this …
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- 19 Feb, 2024
- 6 locations
Locally Advanced Colorectal Cancer and Local Recurrences in V stra G taland
The aim of this study is to review the treatment strategies of locally advanced colorectal cancer and locally recurrent rectal cancer in Vstra Gtaland during 1995-2016. The aim is to evaluate time trends and outcome both related to morbidity and cancer specific survival, we will also evaluate the results after …
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- 19 Feb, 2024
- 1 location
Improving Colonoscopy Quality for Colorectal Cancer Screening in the National VA Healthcare System
High quality screening colonoscopy is critical for colorectal cancer (CRC) prevention in Veterans. There is significant variability in colonoscopy quality in VA that is directly linked to differences in CRC incidence and death. The investigators developed the VA Endoscopy Quality Improvement Program (VA-EQuIP) that the National GI program office will …
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- 19 Feb, 2024
- 2 locations
BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer
The BESPOKE CRC study will prospectively enroll patients who have undergone surgery for stage II or III colorectal cancer (CRC) and who have residual formalin-fixed paraffin-embedded (FFPE) tissue available will provide FFPE and whole blood samples. Patients will receive SIGNATERA test results and may be recommended for adjuvant chemotherapy or …
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- 19 Feb, 2024
- 17 locations
Advanced Geriatric Evaluation and Quality of Life in Colorectal Cancer Surgery
Colorectal cancer (CRC) disproportionately affects patients aged 70 years and older. Surgery is the main treatment modality for CRC, but is associated with increased risk of postoperative morbidity, disability and loss of health related quality of life (HRQL).Frailty is an age related state of functional decline and considered to be …
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- 19 Feb, 2024
- 6 locations
Colorectal Cancer Awareness Research and Education and Screening - Rural Expansion Access and Capacity for Health
This study is to assess the impact of the CARES-REACH intervention on colorectal cancer screening rates.
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- 19 Feb, 2024
- 1 location
A Clinical Study of Pyrotinib in Patients of Advanced Colorectal Cancer With Her2 Variation
To Observe the Efficacy and Safety of Pyrotinib Maleate in Patients With Advanced HER2 Variation Colorectal Cancer
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- 19 Feb, 2024
- 1 location