Chemotherapy Clinical Trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 902 clinical trials
Combination Immunotherapy Targeting Sarcomas

The aim of this clinical trial is to assess the feasibility, safety and efficacy of a combination low dose chemotherapy and immunotherapy in patients who have sarcoma that is relapsed or late staged. Another goal of the study is to assess the safety and efficacy of the therapy that combines …

kidney function tests
immunosuppression
immunosuppressive
creatinine clearance rate
sarcoma
  • 0 views
  • 19 Feb, 2024
  • 2 locations
CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

This phase II trial studies how well liposome-encapsulated daunorubicin-cytarabine (CPX-351) works in treating patients with secondary acute myeloid leukemia who are younger than 60 years old. Drugs used in chemotherapy, such as CPX-351, work in different ways to stop the growth of cancer cells, either by killing the cells, by …

aml
plasma creatinine
secondary acute myeloid leukemia
myelodysplastic syndrome
leukemia
  • 0 views
  • 19 Feb, 2024
  • 1 location
Organ Preservation Program Using Short-Course Radiation & FOLFOXIRI in Rectal Cancer

The purpose of the research is to evaluate whether both chemotherapy and radiotherapy can lead to higher rates of clinical complete response leading to organ preservation in human subjects with cancer.

serum pregnancy test
folfoxiri
total mesorectal excision
chest ct
folfox regimen
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pilot Study of an Implantable Microdevice for Evaluating Drug Responses in Situ in Prostate Cancer

In this research study, is assessing the feasibility of using an MR-guided implantable microdevice to measure tumor response to chemotherapy and other clinically relevant drugs in participants that have prostate cancer and are scheduled for a radical prostatectomy. The name of the study intervention involved in this study is: Implantation …

neutrophil count
carcinoma
prostatectomy
  • 2 views
  • 19 Feb, 2024
  • 1 location
Cross-sectoral Collaboration in Multidisciplinary Treatment of Trauma-affected Refugees

The randomised controlled trial is comparing treatment as usual (TAU) comprising 10 sessions with a medical doctor (pharmacological treatment and psycho-education) and 16-21 sessions with a psychologist (manual-based cognitive behavioural therapy) with add-on of the social intervention.

post-traumatic stress disorder
depression
behavior therapy
cognitive therapy
traumatic stress disorder
  • 0 views
  • 19 Feb, 2024
  • 1 location
Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

All patients will have been previously treated with the standard-of-care treatment which includes surgical resection, radiation and chemotherapy, and in some cases treatment for recurrent disease. Patients with unequivocal recurrence (first or greater) established by MRI and meeting inclusion and exclusion criteria, will be eligible for OKN-007 treatment on this …

  • 0 views
  • 19 Feb, 2024
  • 3 locations
Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

Background Glioblastoma is a type of brain cancer. Treatments include radiation, chemotherapy, and surgery. But survival rates are poor. Researchers think that the drug selinexor, when combined with chemotherapy and radiation, might help.

external beam radiotherapy
blood test
platelet count
gliosarcoma
neutrophil count
  • 0 views
  • 19 Feb, 2024
  • 1 location
AcceleRET Lung Study of Pralsetinib for 1L RET Fusion-positive Metastatic NSCLC

This is an international, randomized, open-label, Phase 3 study designed to evaluate whether the potent and selective RET inhibitor, pralsetinib, improves outcome when compared to a platinum chemotherapy-based regimen chosen by the Investigator from a list of standard of care treatments, as measured primarily by progression free survival (PFS), for …

carboplatin
adjuvant
pralsetinib
metastatic cancer
lung cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Acalabrutinib Lenalidomide and Rituximab for the Treatment of CD20 Positive Stage III-IV Grade 1-3a Follicular Lymphoma

Acalabrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as lenalidomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them …

grade 3 follicular lymphoma
human chorionic gonadotropin
monoclonal antibodies
follicular large cell lymphoma
stage iv grade 1 follicular lymphoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
ATR Inhibitor BAY 1895344 Plus Niraparib Phase 1b Study in Advanced Solid Tumors and Ovarian Cancer

Niraparib works by blocking a substance produced by the body (PARP enzymes) in a way that tumor cells can be killed, or made more susceptible to chemotherapy.

serum pregnancy test
solid tumour
muga scan
platelet count
neutrophil count
  • 0 views
  • 19 Feb, 2024
  • 4 locations