Chemotherapy Clinical Trials

A listing of Chemotherapy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 902 clinical trials
Targeting CD276 (B7-H3) Positive Solid Tumors by 4SCAR-276

Patients with refractory and/or recurrent solid tumor have poor prognosis despite complex multimodel therapy and therefore, novel approaches are urgently needed. This study attempts to treat these diseases using T cells genetically modified with a 4th generation lentiviral chimeric antigen receptor (4SCAR fused with an inducible apoptotic caspase 9 domain) …

tyrosine
serum bilirubin
solid tumor
metastasis
monoclonal antibodies
  • 0 views
  • 19 Feb, 2024
  • 3 locations
Liquid Biopsies and Imaging in Breast Cancer

The aim of the study is to show proof of concept for combining multi-parametric MRI with liquid biopsies in addition to conventional clinical and pathologic information, to accurately predict response to neoadjuvant treatment for patients with primary breast cancer.

trastuzumab
adjuvant therapy
carcinoma
invasive breast cancer
pertuzumab
  • 0 views
  • 19 Feb, 2024
  • 1 location
Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen

Patients eligible for this study have a type of blood cancer Acute Myeloid Leukemia (AML) which has come back or has not gone away after treatment. The body has different ways of fighting disease and infection, and this research study combines two different ways of fighting cancer with antibodies and …

lymphoma
flow cytometry
myeloid leukemia
apheresis
hematologic malignancy
  • 0 views
  • 19 Feb, 2024
  • 1 location
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

Background People with rare cancers often have limited treatment options. The biology of rare cancers is not well understood. Researchers want to find better treatments for these cancers. They want to test 2 drugs that, taken separately, have helped people with non-rare cancers. They want to see if these drugs …

carcinoma, ovarian epithelial
pheochromocytoma, malignant
solid neoplasm
bisphosphonate
mixed mullerian tumors
  • 0 views
  • 19 Feb, 2024
  • 1 location
All-trans Retinoic Acid (ATRA) in the Treatment of Recurrent/Metastatic Adenoid Cystic Carcinoma of the Head and Neck

This is a prospective, open-label, randomized controlled clinical intervention study to evaluate the efficacy and safety of all-trans retinoic acid (ATRA) in treating patients with recurrent metastatic adenoid cystic carcinoma of the head and neck.

measurable disease
spiral computed tomography
ct scan
metastasis
liver metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location
Reduced vs Conventional Dosage Intensity-modulated Radiotherapy for Chemotherapy-sensitive Stage II-III Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that radiotherapy with reduced dose could significantly reduce the incidence of radiotherapy toxicities, improve the quality of life of patients while ensuring the tumor control rates for NPC patients staged as II-III who are sensitive to induction chemotherapy (imaging evaluation …

nasopharyngeal carcinoma
epstein-barr virus dna
creatinine clearance rate
intensity-modulated radiation therapy
karnofsky performance status
  • 6 views
  • 19 Feb, 2024
  • 6 locations
Postoperative Radiotherapy in Breast Cancer- Concurrent or Sequential With Chemotherapy (CONCERT)

This clinical research aims to determine if concurrent chemotherapy and radiation therapy is more effective than sequential chemotherapy and radiation therapy for patients with stage IIB-III breast cancer.

  • 0 views
  • 13 Jun, 2025
Modality of Adjuvant Radiotherapy and Chemotherapy for Stage Endometrial Cancer

The retrospective data of our center showed that the sequential radiochemotherapy of "chemotherapy-radiotherapy-chemotherapy" in the "sanwich" mode could improve the survival outcome in patients with advanced endometrial cancer.

adjuvant radiotherapy
endometrial carcinoma
stage iii endometrial cancer
chemoradiotherapy
adjuvant
  • 0 views
  • 19 Feb, 2024
  • 1 location
FOLFIRINOX vs FLOT Chemotherapy for Resectable Gastric or Esophagogastric Junction Adenocarcinoma

Patients with resectable adenocarcinoma of the stomach or the esophagogastric junction (II-III type by Siewert) without previous therapy will be treated with one of two chemotherapy combinations before and after surgery. One half of the patients gets 5-Fluorouracil (5-FU), Leucovorin, Oxaliplatin and Docetaxel (FLOT), the others 5-Fluorouracil (5-FU), Leucovorin, Oxaliplatin …

hepatitis
leucovorin
combination chemotherapy
cytostatic chemotherapy
folfirinox
  • 0 views
  • 19 Feb, 2024
  • 1 location
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer ALCHEMIST Chemo-IO Study

The purpose of this trial is to find out if the addition of pembrolizumab to usual chemotherapy is better or worse than usual chemotherapy alone for non-small cell lung cancer.

carboplatin
egfr exon 19 deletion
monoclonal antibodies
lung cancer
stage iia lung squamous cell carcinoma ajcc v7
  • 0 views
  • 19 Feb, 2024
  • 359 locations