Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 8027 clinical trials
Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function

Secondary Aims Compare the efficacy of Everolimus plus Mycophenolate Mofetil versus Tacrolimus plus Mycophenolate Mofetil therapy as measured by the following: Biopsy-confirmed acute rejection Hyperlipidemia Proteinuria % regulatory T-cells in circulation NODAT [New Onset Diabetes mellitus After Transplant], hypertension and malignancy Tolerance measured by gene profiling at year 1, 2 …

renal function test
glomerular filtration rate
everolimus
cancer
renal failure
  • 0 views
  • 19 Feb, 2024
  • 1 location
Improving Survivorship Care for Older Adults After Chemotherapy

The researchers want to find out if older adults receiving a survivorship care plan followed by a geriatric assessment visit improves quality of life and satisfaction with care compared to receiving only a survivorship care plan for older adults who have completed chemotherapy for cancer treatment.

  • 0 views
  • 19 Feb, 2024
  • 1 location
the Efficacy and Safety of 5-HT3 Receptor Antagonist Dexamethasone or Megestrol Acetate Dispersible Tablets in the Control of Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy

To compare the efficacy and safety of megestrol acetate dispersible tablets combined with 5-HT3 receptor antagonist and dexamethasone triple antiemetic regimen and 5-HT3 receptor antagonist and dexamethasone combined antiemetic regimen in the control of CINV induced by hyperemetic chemotherapy.

emetic
nausea
dexamethasone
antiemetic
emetics
  • 0 views
  • 19 Feb, 2024
  • 1 location
Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer (TNBC) that has spread, or metastasized, to other parts the body and is PD-L1-negative. The names of the study interventions involved in this study are: Sacituzumab govitecan (IMMU-132) Pembrolizumab (Keytruda; MK-3475)

breast cancer
neuropathy
brain metastases
measurable disease
bisphosphonate
  • 8 views
  • 19 Feb, 2024
  • 1 location
CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

Drugs used in chemotherapy, such as CPX-351, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.

chronic myelomonocytic leukemia
cancer
myelodysplastic syndrome acute myeloid leukemia
t-aml
ejection fraction
  • 0 views
  • 19 Feb, 2024
  • 1 location
Ibrutinib + Venetoclax in Untreated WM

This study evaluates the safety and efficacy of Ibrutinib combined with Venetoclax (IVEN) in the treatment of adults diagnosed with Waldenstrom's macroglobulinemia (WM) cancer with a specific MYD88 gene mutation. This research study involves an experimental drug combination of targeted therapies.

ibrutinib
bone marrow biopsy
igm level
absolute neutrophil count
growth factor
  • 0 views
  • 19 Feb, 2024
  • 2 locations
Radiotherapy Plus Nimotuzumab or Cisplatin in Nasopharyngeal Carcinoma

This is a phase III randomized clinical trial of definitive radiotherapy plus EGFR blocker nimotuzumab versus radiotherapy plus cisplatin(CCRT) for nasopharyngeal carcinoma (NPC) patients with favorable response to induction chemotheray(IC), determining whether radiotherapy combined with nimotuzumab was non-inferior to CCRT and may provide new evidence for individualized comprehensive treatment of …

renal function test
egfr blocker
cancer
carcinoma
EGFR
  • 0 views
  • 19 Feb, 2024
  • 1 location
Pembrolizumab Plus Paclitaxel Cisplatin Followed by Surgery for Locally Advanced ESCC

The purpose of this study is to observe and evaluate the efficacy and safety of pembrolizumab plus paclitaxel, cisplatin followed by Da Vinci robot radical surgery for locally advanced esophageal squamous cell carcinoma.

paclitaxel
carcinoma
urine test
cisplatin
squamous cell carcinoma of esophagus
  • 0 views
  • 19 Feb, 2024
  • 1 location
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma

To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.

renal function test
concurrent radiochemotherapy
cancer
carcinoma
metastasis
  • 0 views
  • 19 Feb, 2024
  • 1 location
SBRT Dose Escalation for Reirradiation of Inoperable Lung Lesions

Prospective phase I study to evaluate the maximum tolerated dose (MTD) of SBRT for thoracic re-irradiation. Dose limiting toxicity will be pneumonitis G3. The potential advantage of the dose escalation planned in this study is the delivery of an ablative dose to radically treat patients with inoperable local relapse, without …

pulmonary metastasis
small cell lung cancer
non-small cell lung cancer
tumor recurrence
pneumonitis
  • 0 views
  • 19 Feb, 2024
  • 1 location