Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 8027 clinical trials
Using Advanced Imaging Studies to Develop a Profile of High-grade Serous Ovarian Cancer

The study researchers will use computers to analyze the combined results of the imaging tests and the genetic and immune system tests on the tumor samples. The study researchers think that this information will help them more accurately predict the way tumors respond to treatment, which may improve their ability …

ovarian carcinoma
ovarian cancer
cancer
carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Neo-TACE-HAIC for BCLC B Stage HCC (Neoconcept)

Pilot study showed TACE combined HAIC (TACE-HAIC) had better tumor response, with low progression disease rate. Whether TACE-HAIC would improve survival for patients with BCLC B stage is need to further to study.

hepatocellular carcinoma
hepatic arterial infusion
carcinoma
liver cancer
chemoembolization
  • 0 views
  • 19 Feb, 2024
  • 1 location
HCC Surveillance: Comparison of Abbreviated Non-contrast MRI and Ultrasound Surveillance in Cirrhotic Patients With Suboptimal Ultrasound Visualisation

All international guidelines recommend 6-monthly ultrasound surveillance for patients at risk for liver cancer (hepatocellular carcinoma or HCC), such as patients with cirrhosis. The aim of surveillance is to detect HCC at an early stage when it is still potentially curable.

hepatocellular carcinoma
liver ultrasound
ascites
encephalopathy
carcinoma
  • 0 views
  • 19 Feb, 2024
  • 10 locations
SBRT Versus Ablation for Perivascular Hepatocellular Carcinoma

This trial is a multi-center, phase III, randomized (1:1) clinical trial. The aim is to explore the efficacy and safety of SBRT for perivascular hepatocellular carcinoma, compared with RFA.

stereotactic body radiation therapy
carcinoma
radiofrequency ablation
recurrent hepatocellular carcinoma
hepatocellular carcinoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
Initial Attack on Latent Metastasis Using TAS-102 for ct DNA Identified Colorectal Cancer Patients After Curative Resection

This trial is a randomized, double-blind, multinational Phase III study to evaluate the efficacy and safety of preemptive treatment with FTD/TPI compared with administration of placebo as follow-up, which is the standard of care, in patients who underwent curative resection of colorectal cancer and then tested positive for ctDNA.

diarrhea
colorectal adenocarcinoma
tas-102
ct scan
trifluridine/tipiracil
  • 0 views
  • 19 Feb, 2024
  • 37 locations
Acalabrutinib Lenalidomide and Rituximab for the Treatment of CD20 Positive Stage III-IV Grade 1-3a Follicular Lymphoma

This phase II trial studies how well acalabrutinib, lenalidomide, and rituximab work in treating patients with CD20 positive stage III-IV, grade 1-3a follicular lymphoma. Acalabrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as lenalidomide, work …

acalabrutinib
grade 3 follicular lymphoma
grade 3a follicular lymphoma
beta-human chorionic gonadotropin
follicular lymphoma
  • 0 views
  • 19 Feb, 2024
  • 1 location
B002 in Patients With HER2-positive Breast Cancer

To assess the safety and tolerability characteristics of B002 in patients with HER2-positive recurrent or metastatic breast cancer. The dose-limiting toxicity (DLT) was assessed and the maximum tolerated dose (MTD) was explored.

monoclonal antibodies
monoclonal antibody therapy
bone metastases
stage iv breast cancer
primary tumor
  • 0 views
  • 19 Feb, 2024
  • 1 location
Safety and Early Signs of Efficacy of IL12-L19L19.

The purpose of this study is to describe the safety, tolerability and early signs of efficacy of the antibody-cytokine fusion protein IL12-L19L19 in patients with advanced or metastatic solid carcinomas and diffuse large B-cell lymphoma (DLBCL), after previous immune checkpoint blockade therapy. The primary objective of the study is to …

squamous cell carcinoma
maintenance therapy
pet/ct
carcinoma
immune checkpoint blockade therapy
  • 0 views
  • 19 Feb, 2024
  • 4 locations
Toripalimab Plus Concurrent Chemo-radiotherapy for Unresectable Locally Recurrent Nasopharyngeal Carcinoma

Through multicenter, open-label, randomised clinical trials, we intend to demonstrate that concurrent and adjuvant PD-1 treatment added to concurrent chemo-radiotherapy could further decrease the rate of disease progression and improve the survival outcome of patients with unresectable locally recurrent nasopharyngeal carcinoma compared with those treated with concurrent chemo-radiotherapy alone.

recurrent nasopharyngeal cancer
toripalimab
carcinoma
karnofsky performance status
nasopharyngeal carcinoma
  • 0 views
  • 19 Feb, 2024
  • 6 locations
ELUCIDATE: Enabling LUng Cancer IDentification Using folATE Receptor Targeting

This is a phase 3, multi-center, single dose, open-label, exploratory study in suspected lung cancer patients scheduled to undergo endoscopic or thoracic surgery per CT/PET/MRI or other imaging based on standard of care. This study aims to assess the efficacy of OTL38 and Near Infrared Imaging (NIR) at identifying pulmonary …

thoracoscopy
pulmonary resection
wedge resection
folic acid
wedge excision
  • 0 views
  • 19 Feb, 2024
  • 5 locations