Neoplasms Clinical Trials

A listing of Neoplasms medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 8039 clinical trials
Memantine for the Reduction of Cognitive Impairment After Radiation Therapy in Pediatric Patients With Central Nervous System Tumors

This early phase I trial studies the feasibility of giving memantine for the reduction of cognitive impairment after radiation therapy in pediatric patients with central nervous system tumors. Memantine may reduce the effects of radiation therapy on memory and thinking.

cognitive impairment
effects of radiation therapy
memantine
pediatric
direct bilirubin
  • 0 views
  • 19 Feb, 2024
  • 1 location
A Study to Evaluate the Safety Pharmacokinetics and Activity of GDC-6036 in Patients With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation

This is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or metastatic solid tumors with a KRAS G12C mutation.

kras g12c mutation
kras
solid tumor
ki-ras
metastatic malignant solid tumor
  • 0 views
  • 19 Feb, 2024
  • 8 locations
Thyroid Cancer and Photoacoustic Imaging

In addition, we would like to confirm the relationship between the results of photoacoustic imaging and histopathologic findings when thyroid nodules were diagnosed as thyroid cancer.

photoacoustic imaging
cancer
thyroid nodule
  • 0 views
  • 19 Feb, 2024
  • 1 location
Study to Assess the Efficacy and Safety of Nivolumab in Combination With Paclitaxel in Subjects With Head and Neck Cancer Unable for Cisplatin-based Chemotherapy (NIVOTAX)

Control arm will be paclitaxel in combination with cetuximab, treatment included in the guidelines of the Spanish Society of Medical Oncology.

neutrophil count
hepatitis c antibody
adjuvant therapy
squamous cell carcinoma of unknown primary
immunodeficiency
  • 0 views
  • 19 Feb, 2024
  • 20 locations
Ipatasertib + Atezolizumab to Prevent Recurrence in TNBC

The purpose of this study is to determine if a combination of two drugs ipatasertib and atezolizumab works as a treatment for residual cancer in the breast or lymph nodes and have circulating tumor DNA in the blood. This research study involves the following investigational drugs: Ipatasertib Atezolizumab

cfdna
axillary lymph node dissection
adjuvant therapy
HER2
serum bilirubin
  • 0 views
  • 19 Feb, 2024
  • 1 location
Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities

This phase I/II trial studies the side effects and best dose of cabozantinib when given with radiation therapy and how well it works in treating patients with sarcoma of the extremities. Cabozantinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Giving …

sarcoma
neutrophil count
hair thinning
gilbert's syndrome
g-csf
  • 0 views
  • 19 Feb, 2024
  • 1 location
cfDNA Methylation Assay for Clinical Evaluation of Patients With Stage IA Lung Cancer After Ablation Operation

The objective is to screen and monitor the efficacy of cfDNA methylation in patients with stage I lung cancer after ablation, to compare the similarities and differences of cfDNA methylation between surgical treatment and ablation in patients with stage I lung cancer, and to look for new indicators to assess …

cfdna
chest ct
lung cancer
ct scan chest
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Patient-Derived Organoids for Rectal Cancer

The purpose of this study is to determine the feasibility of establishing patient-derived organoids from pre-treatment rectal adenocarcinoma biopsies.

adenocarcinoma
proctoscopy
adenocarcinoma of rectum
rectal cancer
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors

This trial studies whether a customized video intervention can help to reduce anxiety in brain cancer patients undergoing radiation treatment and their caregivers. A customized neuro-imaging referenced symptom video that describes symptoms and side effects specific to the patients' tumor may result in an early and sustained reduction in anxiety …

who grade iii glioma
anxiety
karnofsky performance status
glioblastoma multiforme
cancer
  • 0 views
  • 19 Feb, 2024
  • 1 location
Self-Management Survivorship Care in Stage I-III Non-small Cell Lung Cancer or Colorectal Cancer

Participating in the program may improve knowledge and confidence about follow-up care, communication with cancer care and primary care doctors, and quality of life after cancer treatment in non-small cell lung cancer or colorectal cancer survivors.

stage ia3 lung cancer ajcc v8
stage ii lung cancer ajcc v8
stage iib lung cancer ajcc v8
stage iii lung cancer ajcc v8
stage i lung cancer ajcc v8
  • 4 views
  • 19 Feb, 2024
  • 1 location